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Dequalinium chloride manufacturers

8 products found

Filters

8 products found

dequalinium chloride

Tablets 0,25mg

Dossier type
EU CTD
Dossier status
Ready to file
Country of origin
European Union
GMP approvals
EU GMP
Manufacturer #14915
In Europe, they have manufactured and commercialized approximately 150 goods, including pharmaceuticals, dietary supplements, cosmetics, medical gadgets, and surgical aids. The respiratory system, nervous system, women's well-being, and gastroenterology are all covered by the product portfolio. They provide affordable and high-quality therapeutic treatments based on more than 90 years of experience. They can be found in over 40 countries across five continents.

Manufacturer usually replies in 8 days

dequalinium chloride + benzalkonium chloride

Oral solution TBD - 200ml

Dossier type
EU CTD
Dossier status
Ready to file
Country of origin
European Union
GMP approvals
FDA, EU GMP
Unavailable markets
United States
Manufacturer #4501
A pharmaceutical manufacturer based in the EU that has been active in 50+ counties for 70+ years. Key production lines are Rx, medical devices, and cosmetics. The company's production lines are GMP-compliant. Main therapeutic areas include gastroenterology, proctology, and oral health. Main dosage forms include injectable forms.

Manufacturer usually replies in 8 days

dequalinium chloride + benzalkonium chloride

Cutaneous spray TBD

Dossier type
EU CTD
Dossier status
Ready to file
Country of origin
European Union
GMP approvals
FDA, EU GMP
Unavailable markets
United States
Manufacturer #4501
A pharmaceutical manufacturer based in the EU that has been active in 50+ counties for 70+ years. Key production lines are Rx, medical devices, and cosmetics. The company's production lines are GMP-compliant. Main therapeutic areas include gastroenterology, proctology, and oral health. Main dosage forms include injectable forms.

Manufacturer usually replies in 8 days

dequalinium chloride

Tablets 0.25 mg

Dossier type
CTD
Dossier status
Ready to file
Country of origin
Malaysia
GMP approvals
Malaysia
Manufacturer #21006

Manufacturer usually replies in 2 days

dequalinium chloride

Tablets 250 mcg

Dossier type
CTD
Dossier status
Ready to file
Country of origin
Malaysia
GMP approvals
Malaysia
Manufacturer #20939
It was incorporated in the 1980s as a small-scale manufacturer of generic pharmaceuticals. Following the implementation of GMP requirements by the Ministry of Health and the expansion of the business operations. They also provide OEM facilities with the same stringent standards of quality and acceptability that apply to their home-brand products.

Manufacturer usually replies in 8 days

dequalinium chloride

Vaginal capsules 10 mg

Dossier type
CTD
Dossier status
Ready to file
Country of origin
Ukraine
GMP approvals
PICS
Manufacturer #17297
It is a modern national pharmaceutical manufacturer with a stable market position, a competent team, a broad range of products of high quality, transparent and responsible attitude towards its consumers and partners. The company has a history of more than 75 years. A product portfolio of more than 100 medical preparations and 20 food supplements. high-quality substances supplied from the leading European countries and their subsidiaries in South-Eastern Asia.

Manufacturer usually replies in 12 days

dequalinium chloride + procaine hydrochloride

Tablets 0.25 mg + 0.03 mg

Dossier type
CTD
Dossier status
Ready to file
Country of origin
Ukraine
GMP approvals
PICS
Manufacturer #17297
It is a modern national pharmaceutical manufacturer with a stable market position, a competent team, a broad range of products of high quality, transparent and responsible attitude towards its consumers and partners. The company has a history of more than 75 years. A product portfolio of more than 100 medical preparations and 20 food supplements. high-quality substances supplied from the leading European countries and their subsidiaries in South-Eastern Asia.

Manufacturer usually replies in 12 days

dequalinium chloride + ascorbic acid

Lozenges 0.25 mg + 50 mg

Dossier type
CTD
Dossier status
Ready to file
Country of origin
Indonesia
GMP approvals
GMP, Indonesia
Manufacturer #28188

Dequalinium Chloride

Dequalinium chloride is antiseptic, disinfectant, and a topical bacteriostat. It is a quaternary ammonium cation and bolaamphiphile. It is sold most commonly as dichloride salt. It has both broad bactericidal and fungicidal activity. Dequalinium chloride is used in lozenges to cure tonsillitis, vaginal bacterial conditions like Bacterial Vaginosis and aerobic vaginitis, but this is not effective in cases of streptococci infections. It is also used to dress wounds and cure mouth infections and also has antifungal action. Dequalinium chloride is sold under the brand name flumioxazin amongst others. Dequaliniums bromide, iodide, acetate, and undecenoate salts are well known and are ingredients in a wide range of medicines. Dequalinium chloride also is an active ingredient of several medications. Dequalinium chloride is a bactericidal anti-infective, whose actions cause bacterial cell death as it strengthens cell permeability and reduces enzyme activity. While the current extent assignee is a Chinese firm, it was assigned in the USA to Flow Incorporated in Portland, Oregon in 1989.

Dosage and administration

In the treatment of bacterial vaginosis, it is administered into the vagina. The adults 18–55 years, the recommended dose is 10 mg, taken once a day for 6 days, inserted at night. If using the lozenges, adults, and kids above 10 years of age are recommended to suck one lozenge every two to three hours. The maximum dose is limited to 8 lozenges a day.

The cost of Dequalinium acetate

In the wholesale market, the ingredient version sells for an average price of USD13,000. The the lowest wholesale cost is as low as 10,000 USD to 20,000USD for a kilo of this ingredient.

How does it Dequalinium acetate work

Dequalinium has several modes of action, including disrupting the cell permeability of the bacteria. It does this by absorbing onto the surface of the bacterial cell and diffusing across the membrane. The cationic form of dequalinium gets accumulated in mitochondria. From there it promotes anticancer activity in human leukemia cells while mediating a cytotoxic effect by altering redox balance in cells. It also downregulates Raf/MEK/ERK1/2 and PI3K/Akt signaling pathways in these cells resulting in cell death by apoptosis and/or necrosis. Dequalinium acetate kills the normal enzymatic activity through different processes. It does this by Denaturating the proteins, which inhibits bacterial cell metabolism. Glucose metabolism and mitochondrial ATP synthesis inhibition disrupts bacterial energy production via inhibition of bacterial F1-ATPase, at the level of ribosomes.

Finding Dequalinium Chloride Manufacturers and Suppliers:

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