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Dantrolene sodium manufacturers

5 products found

Filters

5 products found

dantrolene sodium

Solution for injection 20MG/VIAL

Dossier type
US CTD
Dossier status
Ready to file
Country of origin
United States
GMP approvals
FDA
Unavailable markets
United States
Manufacturer #4350

Manufacturer usually replies in 5 days

dantrolene sodium

Vials, injection 20 g

Dossier type
CTD
Dossier status
Ready to file
Country of origin
India
GMP approvals
EU GMP
Manufacturer #15176

Manufacturer usually replies in 4 days

dantrolene sodium

Capsules 25 mg, 50 mg, 100 mg

Dossier type
CTD
Dossier status
Ready to file
Country of origin
United States
GMP approvals
FDA
Manufacturer #20737

Manufacturer usually replies in 16 days

dantrolene sodium

Capsules 25 mg

Dossier type
CTD
Dossier status
Ready to file
Country of origin
Taiwan
GMP approvals
PICS
Manufacturer #20504
The company was formed in the 1970s. The company has been holding more than 200 licenses including sugar coating tablets, film coating tablets, enteric coating tablets, granule, powder, capsule, solution, cream, ointment, and suppositories.

Manufacturer usually replies in 10 days

dantrolene sodium

Tablets 25 mg, 50 mg

Dossier type
CTD
Dossier status
Ready to file
Country of origin
India
GMP approvals
WHO
Manufacturer #20401

Manufacturer usually replies in 5 days

Dantrolene Sodium Manufacturers

Dantrolene is a muscle tissue relaxant that is used to treat severe clinical hypermetabolism and malignant hyperthermia crises. Dantrium has indeed been found to cause relaxation in separate nerve-muscle preparations by influencing the muscle's mechanical response at a location further than the myoneural connection. Dantrium disrupts vibrational coupling in muscle tissue, most likely through interfering with Ca2+ discharge from the extracellular space. Signs point to an inherent abnormality of skeletal muscle cells in the general anesthesia malignant hyperthermia syndrome. It's been hypothesized that "triggering substances" cause a shift within the cell, increasing myoplasmic ca in some humans. This increased myoplasmic calcium triggers rapid cellular catabolism, leading to a malignant hyperthermia emergency. Dantrium is thought to restore a reasonable level of ionized calcium in the myoplasm when it is added to "triggered" malignant hyperthermic muscle fibers.

How Does Dantrolene Sodium Work?

By interacting with the adrenergic receptors receptor 1 and reducing intracellular calcium concentration, dantrolene inhibits excitation-contraction coupling in skeletal muscle. The production of calcium from the sarcoplasmic reticulum is mediated by ryanodine receptors, which is an important step in muscle contraction. 5-hydroxydantrolene and an acetylamino metabolite of dantrolene are two of its primary metabolites found in bodily fluids. Another unidentified metabolite appears to be linked to the latter. Dantrium can also be hydrolyzed and then oxidized to generate nitrophenylfuroic acid.

Wholesale Price of Dantrolene Sodium

price varies based on the supplier, a supply of 30 dantrolene oral capsules 25 mg costs roughly $28. Dantrolene Sodium is available for sale from a variety of vendors at a range of costs. Prices are applicable just for cash consumers and do not apply to insurance policies. Dantrolene Sodium suppliers, on the whole, are in favor of patient aid initiatives. This cost may differ among dealers. Its price may vary depending on the country of origin, wholesale costs incurred by manufacturing companies, supplier pricing.

Navigating our Pharmaceutical Marketplace

Being a global B2B pharmaceutical online marketplace, Pipelinepharma is structured to simplify pharmaceutical deals by providing you with an intuitive interface that is easy to engage with. The selection of Dantrolene Sodium offerings can be narrowed down with the use of filters and easily weighed against one another according to medication prices and commercial terms. The advanced filters help you filter out the countries for this substance manufacturer and Dantrolene Sodium suppliers that you are looking for. These also enable you to check the dossier status of this medicine, and the GMP approvals of the different variants of Dantrolene Sodium. Also, each manufacturer or supplier product description contains essential information about this substance including clinical data, stability zones, countries where Dantrolene Sodium is already registered in. Manufacturers also have special, and delivery terms.

Establishing Commercial Ties

If you are a pharmaceutical licensing company or a distributor you can enter into deals or negotiations over these medicine offers with manufacturing companies after completing the free registration process and joining our online marketplace. This helps to ensure that you conclude the pharmaceutical deal at a reasonable cost and achieve the best cost/benefit ratio for your company while bypassing lengthy sourcing, negotiation, and order process. Once you have finalized a deal, you can look forward to a long-lasting business relationship with the Dantrolene Sodium suppliers. This way, the marketplace allows you as a distributor to skip the process of making a list of product manufacturers every time you are looking for in-licensing or distribution deals.

Quality Assurance

To keep up to the quality standards other than Good Manufacturing Practice approvals that this medicine manufacturers list has, we qualify their companies before they are boarded on the platform. This allows us to screen Dantrolene Sodium manufacturers for the quality of the pharmaceutical products’ dossiers and protect against the risk of possible malpractices.