Acute coronary syndrome is treated with the thienopyridine family inhibitor Plavix (clopidogrel bisulfate) (ACS). It was created and produced by Bristol-Myers Squibb (BMS) in association with Sanofi-Aventis, and it received its initial FDA (Food and Drug Administration) approval in 1997.
Clopidogrel is used to prevent heart attacks and strokes in persons with conditions that affect the heart causing strokes, or blood circulation diseases like a peripheral vascular disease. It is used in combination with aspirin in the treatment of recently occurring or worsening chest pain which could be a new heart attack or, unstable angina. Clopidogrel keeps blood vessels open while preventing blood clots post-surgical interventions such as after insertion of a cardiac stent. It belongs to a group of prodrugs called antiplatelet medication. Clopidogrel is sold under the brand name Plavix among others. Clopidogrel was first patented in 1982 and approved for commercial sales in 1997. With more than 20 million prescriptions in the USA alone, it is on the World Health Organization's List of Essential Medicines.
It stops platelets, a kind of blood cell, from congregating and creating a potentially harmful blood clot. If you have a higher risk of developing blood clots, using clopidogrel helps. If you currently have or have had a heart attack, your risk is increased.
Clopidogrel is sold as a tablet in the strengths of 75 mg and 300 mg and is administered orally. The patients start to feel the effect within 2 hours and can last up to 5 days. in the treatment of heart angina, the loading dose is 300 mg with a 75 mg maintenance dose and the treatment of myocardial infractions, 325 mg of Clopidogrel is given in combination with Aspirin.
The generic version of Plavix, clopidogrel, is also used to treat people who have recently experienced a heart attack. Clopidogrel aids us in the following ways: - It is employed in the prevention of heart attacks and strokes.
How does Clopidogrel work?
Clopidogrel effectively blocks platelets from sticking together thus preventing them from forming harmful clots. Additionally, It ensures that the blood keeps flowing smoothly through the body. Clopidogrel is a prodrug, which is activated in two steps, first by Platelet inhibition has been demonstrated two hours after a single dose of oral clopidogrel. It can take some time for the medication to take effect, so in case of new patients or where rapid relief is sought tend to be given a loading dose of either 600 or 300 mg.
The Cost of Clopidogrel
An online search for the wholesale price for sale of Clopidogrel for distributors will reveal a wide range of costs. It will vary from store to store depending on your visit and the country of the wholesale market. For the consumers in the USA, the average cost of Clopidogrel 75mg tablet is $0.75, with the lowest starting at $.40. For the same medication, consumers in the UK pay 0.6 pounds. In India, a generic brand of Clopidogrel costs $0.14 per 75mg tablet.
Navigating our pharmaceutical marketplace
Being a global B2B pharmaceutical online marketplace, Pipelinepharma is structured to simplify pharmaceutical deals by providing you with an intuitive interface that is easy to engage with. The selection of Clopidogrel distributors offerings can be narrowed down with the use of filters and easily weighed against one another according to medication prices and commercial terms. The advanced filters help you filter out the countries for these substance manufacturers and this substance Clopidogrel suppliers that you are looking for. These also enable you to check the dossier status of this medicine and the GMP approvals of the different variants of Clopidogrel. Also, each manufacturer or supplier product description contains essential information about this substance including clinical data, stability zones, countries where Clopidogrel is already registered in. Manufacturers also have special, and delivery terms.
Establishing commercial ties
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