Cimetidine is a medication primarily used to treat heartburn and peptic ulcers, but also a wide range of other conditions, including but not limited to laryngopharyngeal reflux, and Zollinger-Ellison syndrome. H2 blockers are a class of drugs that includes cimetidine. It lessens the production of stomach acid. Suppliers of cimetidine market it in the form of 200mg, 400mg, 800mg oral tablets, although it is also available in 200mg/5ml oral solution. It was first introduced into commercial use in 1977 by the developer and earliest cimetidine manufacturer GlaxoSmithKline. Since then, it has become available in over 100 countries and became the first drug to exceed 1 billion in yearly sales. Currently, numerous manufacturers and suppliers of cimetidine produce their own generic as well as trade name formulations of the drug. The largest manufacturers of cimetidine globally are Union Quimico Farmaceutica, Apotex Pharmachem, and Corden Pharma Bergamo The main alternatives to cimetidine are the other two H2 receptor-positive antagonists – ranitidine and famotidine.
How Does Cimetidine Work?
The actions of histamine are blocked by cimetidine when it binds to an H2-receptor on the basolateral membrane of the stomach parietal cell. Reduced stomach acid output, decreased gastrointestinal volume, and decreased acidity are all effects of this competitive inhibition. Numerous isoenzymes of the hepatic CYP450 enzymes involved are inhibited by cimetidine. An increase in the gastrointestinal bacterial flora, such as nitrate-reducing organisms, is one of Cimetidine's additional effects. The bulk of the parent medication, cimetidine, is removed unchanged in urine following intravenous treatment. The main metabolite of cimetidine, cimetidine sulfoxide, accounts for around 10-15% of complete abolition.
Wholesale Price of Cimetidine
Regardless on the drugstore you go to, a prescription of 10 cimetidine oral medication 400 mg costs about $16. The price of Cimetidine is higher than that of such substitutes, owing largely to the more costly manufacturing process needed to produce it. Also, the costs of Cimetidine vary depending on manufacturer and supplier pricing, whether it is a generic or trade name formulation, concentration of the active ingredient in the formulation. It is available or sale at every medical store. Cimetidine suppliers, on the whole, are in favor of patient aid initiatives. Cimetidine is available for sale from various Cimetidine vendors at multiple costs. Explore the offers of Cimetidine from vendors on our pharmaceutical marketplace or to look up more essential online information about Cimetidine.
From Where to Get Cimetidine?
Finding reliable suppliers and manufacturers of particular medications like Cimetidine can typically be a time-consuming challenge, but with Pipelinepharma's straightforward search engine and network of tested partners, the entire process becomes much simpler. Pharmaceutical specialists are welcome to browse through offers of Cimetidine in our B2B pharmaceutical marketplace, or else find more information about Cimetidine online. Making use of Pipelinepharma's worldwide B2B online marketplace for medications and other pharmaceuticals is the ideal approach to locate and acquire access to Cimetidine manufacturers and suppliers. Utilizing our built-in search engine, all you have to do to begin going is start looking for potential Cimetidine suppliers or manufacturers. You may also use filters to narrow down your search results and look for Cimetidine from particular nations.
Navigating our Pharmaceutical Marketplace
Being a global B2B pharmaceutical online marketplace, Pipelinepharma is structured to simplify pharmaceutical deals by providing you with an intuitive interface that is easy to engage with. The selection of Cimetidine offerings can be narrowed down with filters and easily weighed against one another according to medication prices and commercial terms. The advanced filters help you filter out the countries for this substance manufacturer and Cimetidine suppliers that you are looking for. These also enable you to check the dossier status of this medicine and the GMP approvals of the different variants of Cimetidine. Also, each manufacturer or supplier product description contains essential information about this substance, including clinical data, stability zones, and countries in which Cimetidine is already registered. Manufacturers also have special delivery terms.
Establishing Commercial Ties
Suppose you are a pharmaceutical licensing company or a distributor. In that case, you can enter into deals or negotiations over these medicine offers with manufacturing companies after completing the free registration process and joining our online marketplace. This helps ensure that you conclude the pharmaceutical deal at a reasonable cost and achieve the best cost/benefit ratio for your company while bypassing lengthy sourcing, negotiation, and order process. Once you have finalized a deal, you can look forward to a long-lasting business relationship with the Cimetidine suppliers. This way, the marketplace allows you as a distributor to skip the process of making a list of product manufacturers every time you are looking for in-licensing or distribution deals.
To keep up to the quality standards other than Good Manufacturing Practice approvals that this medicine manufacturers list has, we qualify their companies before they are boarded on the platform. This allows us to screen Cimetidine manufacturers for the quality of the pharmaceutical products' dossiers and protect against the risk of possible malpractices.