Cabergoline is used to treat conditions in which the body produces high levels of prolactin, a
natural substance that helps New mothers lactate but it also known to cause symptoms of
infertility, sexual problems, and bone loss in women or men. Cabergoline is often used as a
first-line agent in the management of Pro-lactinomas due to its higher affinity for D2 receptor
sites, rare side effects, and convenient dosing schedule than other similar medication.
Cabergoline belongs to a class of medications named ‘dopamine receptor agonists’. They
help the body cure by decreasing the amount of prolactin in the body. Cabergoline is
prescribed for Lactation suppression, used as adjunctive therapy of pituitary gland tumours, in
the monotherapy of Parkinson's disease in the early onset, and in combination with other
drugs are also used in the treatment of progressive-phase Parkinson's disease and in the treatment of Uterine fibroids.
Though in pregnancy bromocriptine is often still chosen since there is less data on safety in
pregnancy for cabergoline.
Cabergoline is sold popularly as Cabaser, Dostinex amongst other brand names. Given it
world wide applications, it is manufactured and sold by many manufacturers and is sold
under several other brands names.
Cabergoline was patented first in 1980 and subsequently approved for medical use in 1993.
Italian drug company Farmitalia-Carlo Erba while experimenting with semisynthetic
derivatives of the ergot alkaloids first synthesized it. Farmitalia-Carlo Erba was bought by
Pharmacia, which in turn was bought by Pfizer in 2003, thus owing the patent. Cabergoline,
was first marketed in 1992, as Dostinex in The Netherlands. It drug was approved by the
FDA in 1996 and became generic in 2005 following US patent expiration.
Forms and Dosage
Cabergoline is sold as Tablet in the standard strength of 500mg per pill. In the treatment of
idiopathic and pituitary disorders, the standard dosage for an adults starts with a dose of
250mg pills, taken twice a day.
Cost of Cabergoline
A consumer will pay USD 22 for each pill of 500mg prescription strength in the USA,
whereas in the UK, the consumer will have to pay only 4.20 pounds for the same pill.
In developing countries such as India, the tablet costs USD1,
How does Cabergoline work?
Cabergoline belongs to a class of medicines called dopamine agonists. These dopamine
agonists are drugs are often used to treat similar conditions. Our bodies produce dopamine
which prevents our bodies from releasing prolactin. Cabergoline binds itself to the dopamine
receptors. This binding also prevents the body from releasing prolactin thus decreasing
Finding Cabergoline Manufacturers and Cabergoline Suppliers
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