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Country of origin : Tunisia

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cabergoline

Syrup 0.5mg

Dossier type
CTD
Dossier status
Ready to file
Country of origin
Tunisia
GMP approvals
WHO
Manufacturer #17181

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Cabergoline

Cabergoline is used to treat conditions in which the body produces high levels of prolactin, a natural substance that helps New mothers lactate but it also known to cause symptoms of infertility, sexual problems, and bone loss in women or men. Cabergoline is often used as a first-line agent in the management of Pro-lactinomas due to its higher affinity for D2 receptor sites, rare side effects, and convenient dosing schedule than other similar medication. Cabergoline belongs to a class of medications named ‘dopamine receptor agonists’. They help the body cure by decreasing the amount of prolactin in the body. Cabergoline is prescribed for Lactation suppression, used as adjunctive therapy of pituitary gland tumours, in the monotherapy of Parkinson's disease in the early onset, and in combination with other drugs are also used in the treatment of progressive-phase Parkinson's disease and in the treatment of Uterine fibroids. Though in pregnancy bromocriptine is often still chosen since there is less data on safety in pregnancy for cabergoline.
Cabergoline is sold popularly as Cabaser, Dostinex amongst other brand names. Given it world wide applications, it is manufactured and sold by many manufacturers and is sold under several other brands names.
Cabergoline was patented first in 1980 and subsequently approved for medical use in 1993. Italian drug company Farmitalia-Carlo Erba while experimenting with semisynthetic derivatives of the ergot alkaloids first synthesized it. Farmitalia-Carlo Erba was bought by Pharmacia, which in turn was bought by Pfizer in 2003, thus owing the patent. Cabergoline, was first marketed in 1992, as Dostinex in The Netherlands. It drug was approved by the FDA in 1996 and became generic in 2005 following US patent expiration.

Forms and Dosage

Cabergoline is sold as Tablet in the standard strength of 500mg per pill. In the treatment of idiopathic and pituitary disorders, the standard dosage for an adults starts with a dose of 250mg pills, taken twice a day.

Cost of Cabergoline

A consumer will pay USD 22 for each pill of 500mg prescription strength in the USA, whereas in the UK, the consumer will have to pay only 4.20 pounds for the same pill. In developing countries such as India, the tablet costs USD1,

How does Cabergoline work?

Cabergoline belongs to a class of medicines called dopamine agonists. These dopamine agonists are drugs are often used to treat similar conditions. Our bodies produce dopamine which prevents our bodies from releasing prolactin. Cabergoline binds itself to the dopamine receptors. This binding also prevents the body from releasing prolactin thus decreasing prolactin levels.

Finding Cabergoline Manufacturers and Cabergoline Suppliers

One of the fastest and easiest ways to find Cabergoline manufacturers and Cabergoline suppliers is to make use of Pipelinepharma's global B2B online marketplace for medicines and other pharmaceuticals. Usually, finding trusted manufacturers and supplies of specific drugs like Cabergoline can be a time-consuming challenge, but with Pipelinepharma's simple search engine and network of proven partners, the whole process becomes a lot easier. All you need to do to get started is make use of our integrated search engine and start looking for suppliers or manufacturers of Cabergoline to work with. You can fine-tune your search results using various filters too, letting you search for Cabergoline from specific countries, for example.