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Biphasic isophane insulin manufacturers

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1 products found

biphasic isophane insulin

Injection 300 IU/3 ml

Dossier type
CTD
Dossier status
Ready to file
Country of origin
China
GMP approvals
China
Manufacturer #2715

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Biphasic isophane insulin:

Biphasic isophane insulin, commonly called Humulin M3, is an intermediate-acting insulin for the control of blood sugar in people with diabetes. Insulin is the predominant hormone responsible for regulating blood sugar levels and it has a long history of medicinal use for the treatment of diabetes. Which is characterized by elevated levels of blood glucose, caused by its non-regulation by insulin. Originally produced by the drugs manufacturing company Nordisk Insulin laboratorium in 1923 and following refinement in subsequent years, in 1946 Nordisk formed crystals of protamine and insulin and put it on the medical marketplace in 1950. This new form was called neutral protamine Hagedorn (NPH) insulin, also known as biphasic isophane insulin, which although taking longer to act, continues to act for longer conferring additional benefits.
Currently, biphasic isophane insulin manufacturers and biphasic isophane insulin suppliers list it for sale to distributors on the global marketplace, where it can be found for wholesale at varying price points. This is, in a large part, driven by it being on the World Health Organization's List of Essential Medicines, indicating it as a cost-effective and efficient medication recommended for use in health systems around the globe.

Method of action of biphasic isophane insulin:

Biphasic isophane insulin belongs to a group of pharmaceutical products in the insulin family and as such, they predominantly function through similar pathways. As an outline, post-injection, it initially binds to the insulin receptors on cells located in the body. This triggers the liver, muscle, and fat cells to increase their uptake of glucose from the bloodstream, while also decreasing the production of glucose by the liver and triggering various downstream effects. As glucose is removed from the bloodstream, this reduces blood sugar levels. Therefore, excess blood sugar in ailments such as diabetes can be controlled through the modulated addition of insulin.

Form and dosage of biphasic isophane insulin:

As with all drugs, the final form and packaging is dependent on the specific manufacturers and suppliers, as well as the intended distributor and order. However, it can typically be found for both wholesale and sale in forms including suspension for injection, solution of injection, prefilled syringe, vials, and concentration for infusion for injection. This is a prescription medication, as such, it should only be taken if recommended by a medical professional. Typical dosages will vary upon the individual patient and their need, however, typically it is taken once or twice a day subcutaneously at 100 units/mL. With its effects having an onset of 1–4 hours and its peak being 6–10 hours, with a duration of approximately 10–16 hours.

Biphasic isophane insulin on Pipelinepharma:

Currently, we have found a list of 1 trusted biphasic isophane insulin manufacturers and biphasic isophane insulin suppliers from our global online list of B2B wholesale sellers, located in countries including the European Union. These manufacturers and suppliers have been verified by the Pipelinepharma team, in a time consuming and cost intensive manner, therefore it is likely that there are other distributors awaiting approval. As such, they may appear shortly, as the list is constantly being updated.

Price of biphasic isophane insulin and how to buy:

A cursory search online reveals that Humulin M3 100units/mL suspension for injection (3mL) is typically sold at a wholesale cost of USD 24.71 to the NHS. This is, however, highly dependent on many factors such as location, organisation, and manufacturers. Although the cost of purchase is confidential between both B2B parties on the Pipelinepharma online marketplace, purchase and price inquiries can easily be submitted through the inbuilt interface.

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