Balsalazide Manufacturers

Balsalazide is an anti-inflammatory drug belongs to a class of drugs called aminosalicylates. This drug is used in the treatment of inflammatory bowel disease like ulcerative colitis. It reduces the symptoms of ulcerative colitis such as diarrhea, stomach pain and rectal bleeding. Balsalazide is advised as a prescription product and generic prescription product. Before using this medication, the risk of taking the drug must be weighed against the benefits it provides. It is always recommended to consult a physician before taking Balsalazide as this medication may interact with other drugs and health problems. Balsalazide is marketed by manufacturers under the brand name of Colazal and Giazo. This drug is available only with the doctor’s prescription and is available in the dosage form of Tablet (film coated) and Capsule which is taken by mouth with or without food. Balsalazide is available in dosage strength of 750 mg and 1.1 g The Colazal brand of Balsalazide is used to treat mild to moderate active ulcerative colitis in adults and patients 5 years of age and older and the Giazo brand of Balsalazide is used to treat mild and moderate ulcerative colitis in patients 18 years of age and older . The recommended initial dose in adults for active ulcerative colitis is three 750 mg Balsalazide capsules three times a day i.e. (6.75 g per day) for up to 8 weeks or three 1.1 g tablets twice a day i.e. (6.6 g per day) for up to 8 weeks. The usual dose in pediatrics, aged 5 - 17 years for the treatment of active ulcerative colitis is either three 750 mg Balsalazide capsules three times a day i.e. (6.75 g per day) for up to 8 weeks or one 750 mg Balsalazide capsule 3 times a day (2.25 g per day) for up to 8 weeks. Balsalazide is recommended to store at 20° C to 25° C (68° F - 77° F), with excursion permitted between 15° C to 30° C (59° F - 86° F).

Wholesale Price of Balsalazide

The wholesale price for Balsalazide oral capsule 750 mg is around $ 31 for a supply of 30 tablets with per unit cost available at $ 1.03 For a set of 280 Balsalazide oral capsule 750 mg it costs approximately between $ 151.56 - $ 210.31 with a per unit price available at as low as $ 0.54 – 0.75

Balsalazide - Mechanism of Action

Balsalazide is a prodrug that had little or no pharmacologic activity until it is enzymatically divided in the colon to produce mesalamine (5-aminosalicylic acid), an anti-inflammatory drug indicated for the treatment of mild to moderate active ulcerative colitis. Balsalazide is released intact in to the colon, where it is divided by bacterial azoreduction to release mesalamine, which is therapeutic active portion of the molecule. This 5-aminosalicylic acid exerts its anti-inflammatory effects locally in the gastrointestinal tract by blocking production of arachidonic acid metabolites in the colon through both the inhibition of cyclooxygenase and lipoxygenase.

Finding Balsalazide Manufacturers and Suppliers

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