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Apomorphine manufacturers

12 products found

Filters

12 products found

apomorphine

Solution for infusion 5 mg/ml - 10 ml

Dossier type
EU CTD
Dossier status
Ready to file
Country of origin
European Union
GMP approvals
EU GMP
Available for
Distribution only
Comments
Ref: APO-go®
Manufacturer #10720

It is one of the oldest pharmaceutical companies specializing in generic mostly for the hospital segment. The key products offered are life-saving medicines, especially in the CNS and cardiovascular therapeutic group. The company follows and complies with the EU GMP requirements.

Manufacturer usually replies in 4 days

apomorphine

Ampoules, injection 10 mg / 1 ml, 100 mg / 10 ml

Dossier type
EU CTD
Dossier status
Ready to file
Country of origin
Switzerland
GMP approvals
EU GMP
Manufacturer #17475
A major European seller who has spent more than 40 years in the medicine and pharmaceutical industry. Right from ancillary business to pharmaceutical sellers, they have been revolutionary in each and every field

Manufacturer usually replies in 9 days

apomorphine

Solution for injection/infusion 50 mg/5 ml, 100 mg/20 ml, 30 mg/3 ml

Dossier type
EU CTD
Dossier status
Ready to file
Country of origin
European Union
GMP approvals
EU GMP
Unavailable markets
Denmark , Finland , Iceland , Norway , Sweden
Available for
Distribution only
Manufacturer #12922

Manufacturer usually replies in 7 days

apomorphine

Solution for injection 30MG/3ML (10MG/ML)

Dossier type
US CTD
Dossier status
Ready to file
Country of origin
United States
GMP approvals
FDA
Unavailable markets
United States
Manufacturer #4350

Manufacturer usually replies in 5 days

apomorphine

Injection, pre-filled pen 30mg in 3ml

Dossier type
EU CTD
Dossier status
Ready to file
Country of origin
European Union
GMP approvals
EU GMP
Manufacturer #5670

apomorphine

Ampoules, injection 50mg in 10ml

Dossier type
EU CTD
Dossier status
Ready to file
Country of origin
European Union
GMP approvals
EU GMP
Manufacturer #5670

apomorphine

Ampoules 10 mg/ml - 5 ml

Dossier type
EU CTD
Dossier status
Ready to file
Country of origin
Switzerland
GMP approvals
EU GMP
Manufacturer #8501

A pharmaceutical manufacturer based in Europe that has been active in 10+ countries selling its products in Europe, North America, and Asia for 100+ years. The company's production lines are cGMP-compliant. The main dosage forms include injectable and oral solid. The company possesses manufacturing facilities in Europe, North America, and Asia.

Manufacturer usually replies in 5 days

apomorphine

Solution for injection 50 mg/5 ml, 20 mg/2 ml - 5 ml, 2 ml

Dossier type
CTD
Dossier status
Ready to file
Country of origin
Turkey
GMP approvals
EU GMP, PICS
Manufacturer #2760

Manufacturer usually replies in 5 days

apomorphine

Ampoules, injection 10 mg / ml (1% w / v)

Dossier type
CTD
Dossier status
Ready to file
Country of origin
Turkey
GMP approvals
Turkey
Manufacturer #14913
With over 20 years of expertise, it is Europe's leading specialty pharmaceutical company. They collaborate with international pharmaceutical companies to deliver novel cures and solutions to our community. Working in accordance with ethical and scientific principles, the company aims to set the highest standards for quality, safety, and value in the manufacturing and distribution of healthcare goods.

Manufacturer usually replies in 9 days

apomorphine

Solution for injection 10 mg/ml - 2 ml

Dossier type
CTD
Dossier status
Ready to file
Country of origin
India
GMP approvals
PICS
Manufacturer #10242

Manufacturer usually replies in 9 days

apomorphine

Ampoules, injection 20mg/2ml, 50mg/5ml

Dossier type
CTD
Dossier status
Ready to file
Country of origin
Turkey
GMP approvals
PICS
Manufacturer #16290
The leading pharmaceutical company that provides patient care and services at its no. 1 specialty. The company is known to cover national as well as international markets and always relies on R&D to update its products.

Manufacturer usually replies in 60 days

apomorphine

Ampoules 20 mg/2 ml, 50 mg/5 ml

Dossier type
CTD
Dossier status
Ready to file
Country of origin
Turkey
GMP approvals
PICS
Manufacturer #1430

Manufacturer usually replies in nan days

Apomorphine

Apomorphine is used to treat intermittent hypomobility in Patients with advanced Parkinson's disease. In this condition, the individual sees a decreased response to an anti-Parkinson drug such as L-DOPA causing muscle stiffness and loss of muscle control. Apomorphine is given in combination L-DOPA with the intention to reduce the L-DOPA dosing, because those at the advanced stages often have many of dyskinesias associcated with L-DOPA and periods of hypermobility. The apomorphine is injected subcutaneously, when an episode sets in, and signs subside. Patients can use portable mini-pumps to continuously infuse apomorphine, an average of three times a day, allowing them to stay in the "on" state. Apomorphine is called dopamine agonists. They works by acting like dopamine, which our minds need to motor control. In patients with advanced stage of Parkinsons, the ''off'' episodes, when they have difficulty moving, walking, and speaking, occur as medication wears off or at random who have been taking other therapies for a long and are taking other medications for their condition. Apomorphine is available under the brand name Apokyn among others. Apomorphine was first synthesised by Arppe in 1845 from morphine and sulfuric acid.. Earlier, in 1869, Matthiesen and Wright has used hydrochloric acid instead of sulfuric acid in the process, naming the resulting compound apomorphine.

Dosage and administration

Apomorphine solution is available as a glass cartridge and it comes with an injector pen. You will be given some needs with the pen, however, the patient is also recommended to buy a few more, any questions about administration must be cleared with the doctor, including the needle to be used. Patients must always use a new, sterile needle for every injection. These needles once used must be immediately destroyed, and never used again. They can also not touch any surface except the exact spot of the injection. Injector pen must be never be carried or stored with the needle attached. Use puncture-resistant container and learn from the pharmacist about how to discard the puncture-resistant container. It can be injected in stomach, upper arm, or upper leg areas. You will also be given other medication to help decrease your chance of developing nausea and vomiting while you are using apomorphine injection, more so during the beginning of treatment. Patients are usually started off on a low dose. The dose is gradually increased, not more than once every few days. If you want to stop using the medication, do not do it without consulting your doctor.

The Cost of Apomorphine

In the USA, the consumers have to pay and average retail price of $42 for 3 mL pen. In the USA, the Average Daily Drug Cost of using this medicine is USD 4.30 to 21.48. this medicine also relatively economical to buy in the developing world. In India, the injections are available in 2 ml and 5 ml ampoules cost USD4 and USD9, respectively. With daily cost between USD7 and USD15.

How does Apomorphine Work?

As a non-ergoline dopamine agonist, Apomorphine has high binding affinity to dopamine D2, D3, and D5 receptors. Caudate-putamen, a region of the brain responsible for locomotor control is achieved through stimulation of D2 receptors in the brain. The eventual result is that relaxation of the stiffness and better motor control in individuals.

Finding Apomorphine Manufacturers and Suppliers:

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