Aceclofenac is a pain-relief medication used to manage inflammation and pain in patients with rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis. It is used in standalone medications as well as in combination drugs along with ingredients such as serrapeptase, paracetamol, thiocolchicoside, and others. The drug is marketed as aceclofenac tablets. Aceclofenac was developed as an analog to diclofenac to produce a drug with the same efficacy and superior gastrointestinal tolerability. First approved in 1992, it has since then become more popular to its forerunner in Europe. More than 100 different medications that contain aceclofenac are currently produced by various manufacturing companies internationally. Major pharmaceutical manufacturers and suppliers of aceclofenac include Accord Healthcare, Mylan, and Gideon Richter. Suppliers market both generic and trade name medications with aceclofenac.
How Does Aceclofenac Work?
Aceclofenac reduces the production of a number of inflammatory mediators, such as prostaglandin E2, IL-1, and TNF, from the arachidonic route by inhibiting COX-2. The conversion of aceclofenac to diclofenac is assumed to be the mechanism by which IL-6 is inhibited. Reactive oxygen species are produced less when the inflammatory cytokines are suppressed. Human articular chondrocytes' nitrous oxide production has been demonstrated to be reduced by aceclofenac. By reducing the production of L-selectin, a cell adhesion compound produced by lymphocytes, aceclofenac inhibits neutrophil adherence to endothelium. It is hypothesised that aceclofenac stimulates glycosaminoglycan synthesis, possibly through its inhibition of IL-1 synthesis and activity. Because 4'-hydroxyaceclofenac prevents chrondrocytes from releasing proteoglycan, it has chrondroprotective properties.
Wholesale Price of Aceclofenac
The retail price of 20 100mg aceclofenac tablets is approximately 5-6 EUR. The costs of Aceclofenac vary depending on manufacturer and supplier pricing, whether it is a generic or trade name formulation, concentration of the active ingredient in the formulation. Aceclofenac is available for sale from various Aceclofenac vendors at various costs. The prices of Aceclofenac medications vary depending on the concentration of active ingredients in the formulation as well as supplier and manufacturer pricing. The price of Aceclofenac is higher than that of such substitutes, owing largely to the more costly manufacturing process needed to produce it. Aceclofenac suppliers, on the whole, are in favor of patient aid initiatives.
From Where to Get Aceclofenac?
Buyers are advised that online sellers may attempt to market fraudulent versions of the generic drug, whereas Pipeline Pharma, through its pre-auditing and quality control procedures ensures that only verified Aceclofenac manufacturers and wholesalers enter our online marketplace, offering you a risk-free B2B pharmaceutical sales platform. Making use of Pipelinepharma's worldwide B2B online marketplace for medications and other pharmaceuticals is the ideal approach to locate and acquire access to Aceclofenac manufacturers and suppliers. Finding reliable suppliers and manufacturers of particular medications like Aceclofenac can typically be a time-consuming challenge, but with Pipelinepharma's straightforward search engine and network of tested partners, the entire process becomes much simpler. Utilizing our built-in search engine, all you have to do to begin going is start looking for potential Aceclofenac suppliers or manufacturers. You may also use filters to narrow down your search results and look for Aceclofenac from particular nations.
Navigating our Pharmaceutical Marketplace
Being a global B2B pharmaceutical online marketplace, Pipelinepharma is structured to simplify pharmaceutical deals by providing you with an intuitive interface that is easy to engage with. The selection of Aceclofenac offerings can be narrowed down with filters and easily weighed against one another according to medication prices and commercial terms. The advanced filters help you filter out the countries for this substance manufacturer and Aceclofenac suppliers that you are looking for. These also enable you to check the dossier status of this medicine and the GMP approvals of the different variants of Aceclofenac. Also, each manufacturer or supplier product description contains essential information about this substance, including clinical data, stability zones, and countries in which Aceclofenac is already registered. Manufacturers also have special delivery terms.
Establishing Commercial Ties
Suppose you are a pharmaceutical licensing company or a distributor. In that case, you can enter into deals or negotiations over these medicine offers with manufacturing companies after completing the free registration process and joining our online marketplace. This helps ensure that you conclude the pharmaceutical deal at a reasonable cost and achieve the best cost/benefit ratio for your company while bypassing lengthy sourcing, negotiation, and order process. Once you have finalized a deal, you can look forward to a long-lasting business relationship with the Aceclofenac suppliers. This way, the marketplace allows you as a distributor to skip the process of making a list of product manufacturers every time you are looking for in-licensing or distribution deals.
To keep up to the quality standards other than Good Manufacturing Practice approvals that this medicine manufacturers list has, we qualify their companies before they are boarded on the platform. This allows us to screen Aceclofenac manufacturers for the quality of the pharmaceutical products' dossiers and protect against the risk of possible malpractices.