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Trimebutine maleate manufacturers

35 products found

Filters

35 products found

trimebutine maleate

Tablets 100 mg, 200 mg - 30'S

Dossier type
EU CTD
Country of origin
European Union
Dossier status
Ready
GMP approvals
EU GMP
Unavailable markets
Vietnam

Manufacturer #11864

A pharmaceutical manufacturer based in the EU that is active in 20+ countries worldwide selling its products in EU, CIS, LATAM, and South-East Asia for 30+ years. Key production lines are Rx medicines, OTC drugs, and dietary supplements with EU GMP certification. The company's main therapeutic areas include oncology, cardiology, psychiatry, and internal medicine. The company provides eCTD format dossiers as well as BE studies and stability studies.

Manufacturer usually replies in 7 days

trimebutine maleate

Capsules 200mg

Dossier type
EU CTD
Country of origin
European Union
Dossier status
Ready
GMP approvals
EU GMP

Manufacturer #16299

The company has a manufacturer’s license for medicinal products for human use authorized by the National Agency of Medicines. The highest quality products are manufactured and packaged in the production units with GMP International Standards and regularly checked by the National Agency of Medicines by the requirements of the European Medicines Agency (EMEA). The principal activity of the company is the production of pharmaceutical products, which are certified with patents, in various forms (tablets, capsules, syrups, oral solutions, powders for liquid compositions, gels, creams, and ointments) and various categories (antibiotics, antifungals, antivirals, anti-inflammatories, analgesics, antipyretics, anxiolytics, antidepressants, bronchodilators, antilipidemics, antitussives, cholinesterase inhibitors, antipsoriatics, antacids, anticholinergics, antidiarrheals, etc.).

Manufacturer usually replies in 15 days

trimebutine maleate

Tablets, film coated 300mg

Dossier type
CTD
Country of origin
European Union
Dossier status
Ready
GMP approvals
EU GMP

Manufacturer #8921

A pharmaceutical manufacturer based in Europe that has been selling its products in Europe, Africa, North America, the Middle East, and CIS for 40+ years. The main therapeutic areas include oncology, allergology, and dermatology. Key production lines are Rx, medical devices, OTC, and nutraceuticals. The main dosage forms include oral solids, oral liquids, and injectables. The company's production lines are EU GMP-compliant.

Manufacturer usually replies in 2 days

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TRIMEBUTINE MALEATE MANUFACTURERS

Trimebutine is a spasmolytic agent. It helps to regulate the intestinal and colonic motility. Thus it relieves the abdominal pain with antimuscarinic and weakens MU opioids against the bad effects. It is generally produced for the treatment of (IBS) also known as irritable bowel syndrome. It helps to lower the gastrointestinal tract motility disorders, with IBS. Which is one of the most common multifactorial GI disorders. This pharmaceutical substance is vastly used in restoring normal bowel function and is commonly present in pharmaceutical mixtures/drugs as the salt form of trimebutine maleate. Although this drug is not an FDA-approved drug, it is accessible in Canada and many other international countries. This spasmolytic agent acts directly on smooth muscle. It modulates gastric motility. It results in a "twofold function" that animates or inhibits uncontrollable contractions which depends on the concentration and prior contractile activity in the preparation. At lower concentrations such as - (1-10uM), it depolarizes the resting membrane potential and does not affect the amplitude of contractions. which is thought to be interfered with by inhibition of visible potassium currents. It is also shown to activate the T-type Ca2+ channel and increases gastric emptying, abdominal and colonic contractility. At higher consistencies like - (100-300uM), it reduces the amplitude of spontaneous contractions, and action potentials are thought to be mediated by repression of L-type Ca2+ channels and internal calcium current. This medicinal substance mediates a regional anesthetic action by acting as a weak agonist at mu-opioid receptors. PipelinePharma has found 10 verified trimebutine maleate manufacturers and trimebutine maleate suppliers from the global list of sellers. The pharmaceutical drug is ready for sale in different forms; such as - tablets, capsules, tablets film-coated, tablets- modified-release (MR), oral suspension, tablets, extended-release (er) from among the manufacturers in various countries including the European Union, Turkey, South Korea, China, Paraguay, Argentina.

HOW DOES TRIMEBUTINE MALEATE WORK?

This is recommended to connect to the inactivated state of the calcium channel with a high resemblance. When reduced down, calcium influx attenuates membrane depolarization and slowly decrease colon peristalsis. It also hinders outward K+ currents in response to membrane depolarization of the GI smooth muscle cells at resting conditions. It works through the inhibition of delayed rectifier K+ channels and Ca2+ dependent K+ channels, which results in effected muscle contractions. Trimebutine binds to mu-opioid receptors with more extended selectivity compared to delta or kappa opioid receptors.

The Wholesale Price of Trimebutine MALEATE

An online search for the wholesale price of TRIMEBUTINE will reveal a wide range of costs. High-quality trimebutine maleate powder CAS 34140-59-5 costs the US $ 20 - 120 / Kilogram on an average.

Sourcing TRIMEBUTINE Manufacturers and Suppliers

Being a global B2B pharmaceutical online marketplace, PipelinePharma is structured so that we can simplify pharmaceutical deals by providing the buyers with an authentic interface that is straightforward to interlock with. The selection of trimebutine maleate offerings can be narrowed down with the use of filters and easily weighed against one another according to medication prices and commercial terms. Buyers are looking for an easy and helpful way to source and order trimebutine can search online using Pipelinepharma's marketplace. Through our strict vetting and quality control procedures, you will only find verified manufacturers and suppliers.