Generics 21

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Selenium manufacturers

21 products found

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21 products found

dihydroartemisinin + selenium + iodine

Capsules 50mg

Dossier type
CTD
Dossier status
Ready to file
Country of origin
European Union
GMP approvals
EU GMP
Registered in
Czech Republic , Denmark , Finland , France , Germany , Greece , Italy , Norway , Poland , Portugal , Romania , Serbia , Slovenia , Spain , Sweden , Russia , United Kingdom , United States , Australia , Austria , Belgium
Available for
Licensing with supply, Distribution only
MAs available in
Czech Republic , Denmark , Finland , France , Germany , Greece , Italy , Norway , Poland , Portugal , Romania , Serbia , Slovenia , Spain , Sweden , Russia , United Kingdom , United States , Australia , Austria , Belgium
Manufacturer #17270
A pharmaceutical manufacturer based in the EU that does production and distribution in Europe. Key production lines are OTC and nutraceuticals. The company's production lines are EU GMP-compliant.

Manufacturer usually replies in 1 days

zinc + histidine + vitamin c + selenium

Granules 10 mg + 50 mg + 100 mg + 50 µg

Dossier type
EU CTD
Dossier status
Ready to file
Country of origin
European Union
GMP approvals
EU GMP
Available for
Licensing with supply
Manufacturer #515
This company, headquartered in the EU, specializes in developing and manufacturing user-friendly oral dosage forms for the pharmaceutical industry. They have over four decades of experience, providing a comprehensive range of services from product design and development to GMP-compliant manufacturing and market launch. Their expertise lies in creating innovative formulations, such as direct granules, chewable tablets, effervescent tablets, instant drinks, and lozenges, catering to diverse patient needs. They focus on delivering solutions for Rx and OTC products, including nutraceuticals, and offer their services for in-licensing and contract manufacturing. Their commitment to innovation and sustainability is evident in their recent €25 million investment to expand capacity and their Silver CSR Award from EcoVadis. The company is actively involved in the global pharmaceutical market, exhibiting at international events like CPHI.

Manufacturer usually replies in 9 days

cupric sulfate + manganese + selenium + zinc sulphate

Vials 0.3 mg + 55 mcg + 60 mcg + 3 mg/ml

Dossier type
EU CTD
Dossier status
Under development
Country of origin
European Union
GMP approvals
EU GMP
Comments
Ref. Tralement®, AM Reagent
Manufacturer #8822
A pharmaceutical manufacturer based in Europe that has been active in 60+ countries selling its products in Europe, North America, LATAM, MENA, and Asia for 50+ years. The main therapeutic areas include CNS, ophthalmology, and dermatology. Main dosage forms include sterile and solid oral dosage forms. The company's production lines are cGMP-compliant. The company possesses branches in Europe, North America, and Asia.

Manufacturer usually replies in 16 days

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Dihydroartemisinin

Dihydroartemisinin or DHA is a semi-synthetic derivative of artemisinin. It is used primarily in the preparation of Artemisinin-derived antimalarial drugs. It cures malaria. While Dihydroartemisinin is the active metabolite in artemisinin compounds it is also sold as a drug in itself. Commercially, it is sold with piperaquine. It has been shown to be similar to Artemether or Lumefantrine. Dihydroartemisinin in combination with piperaquine is sold as Eurartesim and Artekin among several other brands. Hoechst Aktiengesellschaft filed the first patent in 1987, this was followed by a patent filing in the USA by Thornfeldt Carl R in 1987. In 2018, WHO says, worldwide malaria-affected 228 million people, resulting in 405,000 deaths. The key to the treatment is timely intervention before it turns severe and then fatal.

Dosage and forms

Dihydroartemisinin is sold as tablets and injections. In the cases of acute malaria, the initial the recommended adult dose is 120 mg, and this is followed by a maintenance dose of 60 mg, taken daily for another 4 to 6 days.

The cost of Dihydroartemisinin

In India and elsewhere in the developing world this medicine is very cheap. In most countries, a tablet of 200 mg costs less than a cent. The oral suspension costs around USD1 for an 80ml solution.

How does Dihydroartemisinin Work?

Apicomplexans cause Malaria. Plasmodium falciparum residing in red blood cells and contains iron-rich heme-groups. Dihydroartemisinin binds to a large number targets a broad spectrum of proteins in the human cancer cell proteome through heme-activated radical alkylation. Dihydroartemisinin actions cleavage endoperoxide bridges by iron. It does this producing free radicals like hypervalent iron-oxo species, epoxides, aldehydes, and dicarbonyl compounds. These damage biological macromolecules causing oxidative stress in the cells of the parasite. Its production of free radicals, reactive metabolites, and altered membrane transport properties of membranes stop the nutrient flow to the parasite. It is Active against all human malarial parasites, including even the multi-drug resistant Plasmodium falciparum strains.

Finding Dihydroartemisinin Manufacturers and Suppliers:

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