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Country of origin : India
1 products found

pp-201

Tablets

Dossier type
CTD
Dossier status
Under development
Country of origin
India
GMP approvals
India
Comments
Indication: Major depressive disorder (MDD) Clinical stage: Phase 2b — ongoing Modality: Small molecule (first-in-class nAChR antagonist) Mechanism / Target: First-in-class selective α4β2 nicotinic acetylcholine receptor (nAChR) antagonist; modulates cholinergic neurotransmission in limbic circuits to produce antidepressant effects via a mechanism entirely distinct from monoamine reuptake inhibition Route / form: Oral tablet Differentiation: First-in-class nAChR antagonist for MDD; wholly novel cholinergic mechanism independent of serotonin/norepinephrine reuptake or receptor blockade; addresses patients with inadequate response to standard antidepressants;
Manufacturer #39338

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