Olmesartan Medoxomil is a synthetic imidazole derivative prodrug with an antihypertensive property. Olmesartan Medoxomil is a member of biphenyls. Upon hydrolysis, Olmesartan Medoxomil is converted to Olmesartan. Olmesartan belongs to the angiotensin II receptor blocker (ARB) family of drugs. Olmesartan is commonly used for the management of hypertension and Type 2 Diabetes associated nephropathy, heart failure, and post-myocardial infarction particularly in patients who are unable to tolerate ACE inhibitors. Olmesartan is indicated for the treatment of hypertension either alone or in combination with other antihypertensive agents. Manufacturers of Olmesartan Medoxomil market these drugs under the Brand name of Benicar, Olmetec. This drug comes only as a tablet which is taken by mouth. Olmesartan Medoxomil is available in 5 mg, 20 mg, 40 mg dosage strengths. 5 mg tablets are yellow, round, film coated tablets identified by a debossed code “C12” on one side and manufacturer name on the other. 20 mg tablets are white, round, film coated tablets identified by a debossed code “C14” on one side and manufacturer name on the other. 40 mg tablets are white, oval shaped, film coated tablets identified by a debossed code “C15” on one side and manufacturer name on the other. For Hypertension, the usual recommended starting dose of Olmesartan Medoxomil is 20 mg once daily and for patients requiring further reduction in blood pressure after 2 weeks of therapy, the dose may be increased to 40 mg. Dose above 40 mg do not appear to have grater effect. Twice-daily dosing offers no advantage over the same. The approved storage conditions for Olmesartan Medoxomil is at 20° C - 25° C (68° F - 77° F). Wholesale Price of Olmesartan Medoxomil The wholesale price for 30 units of 5 mg Olmesartan Medoxomil oral tablet is approximately $ 57.07 with per unit cost comes at $ 1.90. The lowest available wholesale price for the quantity of 1000 Olmesartan Medoxomil tablets is $ 1595.20 with per unit costs as low as $ 1.60 The per unit cost of 20 mg Olmesartan Medoxomil oral tablet is approximately $ 2.20, which is available for a price of around $ 66.00 for 30 tablets whereas for a set of 90 tablets it costs approximately $ 179.01, with per unit cost $ 1.99 The 40 mg tablets are available at a price range of $ 78.63 - $ 88.04 for a set of 30 tablets with per unit ranges between $ 2.62 - $ 2.93 Olmesartan Medoxomil - Mechanism of Action Olmesartan belongs to the angiotensin II receptor blocker (ARB) family of drugs. ARBs selectively bind to angiotensin receptor 1 (AT1) and prevent the protein angiotensin II from binding and exerting its hypertensive effects. As the principal pressor agent of the renin-angiotensin system, Angiotensin II causes vasoconstriction, stimulation of synthesis and release of aldosterone, cardiac stimulation and renal reabsorption of sodium. Olmesartan blocks the vasoconstrictor effects of angiotensin II by selectively blocking the binding of angiotensin II to the AT1 receptor in vascular smooth muscle. Overall, Olmesartan’s physiologic effect lead to reduced blood pressure, lower aldosterone levels, reduced cardiac activity and increased excretion of sodium. Finding Olmesartan Medoxomil Manufacturers and Suppliers Finding a trustful partner in our business is one of the biggest challenges and to overcome that challenge and to make one’s work / life easy in finding the trusted manufacturer and supplier of Olmesartan Medoxomil one can visit the Pipelinepharma website which helps you in finding the trusted manufacturers and suppliers of Olmesartan Medoxomil. Pipelinepharma, which is a business-to-business (B2B) licensing marketplace for pharmaceutical products that quickly connects owner with the customers for the business development. You can filter the product names in user friendly and unified search engine by its country, category, therapeutic area, forms, dossier and its status, regulatory filings, approvals, and more.