Nebivolol is a cardioselective beta blocker-type medication that is used to treat high blood pressure and heart failure. The drug is marketed in the form of nebivolol oral tablets (at concentrations of 2.5mg, 5mg, 10mg, and 20mg). The recommended dosage for patients is typically one tablet daily. First introduced into the market in 1997, nebivolol is now approved in and distributed to over 50 countries worldwide by a wide range of suppliers. Major international suppliers of nebivolol include Sandoz, Teva, Mylan, Menarini, and The Searle Company.
Nebivolol taken in the morning or evening dramatically lowers 24-hour blood pressure measurements. Evening administration of nebivolol may have a benefit over morning medication in terms of lowering prewaking systolic blood pressure.
Tiredness, headache, stomach upset, and shortness of breath are the most prevalent side effects. Nebivolol treatment is typically long-term. Continue to take the tablets on a regular basis; stopping without first consulting your doctor may result in complications.
How does Nebivolol work?
Nebivolol is a beta-blocker medication. It operates by influencing the reaction to nerve signals in certain areas of the body, such as the heart. As a consequence, the heart beats less and the blood pressure drops. When blood pressure is reduced, the quantity of blood and oxygen delivered to the heart increases.
The only beta-blocker known to stimulate vascular production of nitric oxide, the principal endothelial vasodilator, is nebivolol, a highly selective blocker of beta(1)-adrenergic receptors. Nebivolol's unique mechanism is especially important in hypertension, when nitric oxide impairment occurs.
The Cost of Nebivolol
An online search for the wholesale price for sale of Nebivolol for distributors will reveal a wide range of costs. It will vary from store to store depending on your visit and the country of the wholesale market. The wholesale acquisition cost per month's supply of nebivolol tablets in the U.S. is approximately 128 USD. The retail price in the EU for the same amount ranges from around 3 EUR to 9EUR. Such a large price disparity can be accounted for by the fact that although generic versions of the drug are marketed in many countries internationally, no generic nebivolol manufacturer has been granted marketing authorization in the U.S. Nebivolol is used not only as a single active ingredient in medications but also along with other active substances in combination drugs. For example, one of the more popular branded versions of nebivolol is Nebilet from manufacturers Menarini and Berlin-Chemie. However, the two manufacturing companies also produce a variant of the drug with the active ingredient hydrochlorothiazide under the trade name Nebilet Plus. Buyers are advised that online sellers may attempt to market fraudulent versions of the generic drug, whereas Pipeline Pharma, through its pre-auditing and quality control procedures ensures that only verified manufacturers and wholesalers enter our online marketplace, offering you a risk-free B2B pharmaceutical sales platform.
Navigating our pharmaceutical marketplace
Being a global B2B pharmaceutical online marketplace, Pipelinepharma is structured to simplify pharmaceutical deals by providing you with an intuitive interface that is easy to engage with. The selection of Nebivolol distributors offerings can be narrowed down with the use of filters and easily weighed against one another according to medication prices and commercial terms. The advanced filters help you filter out the countries for these substance manufacturers and this substance Nebivolol suppliers that you are looking for. These also enable you to check the dossier status of this medicine and the GMP approvals of the different variants of Nebivolol. Also, each manufacturer or supplier product description contains essential information about this substance including clinical data, stability zones, countries where Nebivolol is already registered in. Manufacturers also have special, and delivery terms.
Establishing commercial ties
If you are a pharmaceutical licensing company or a distributor you can enter into deals or negotiations over these medicine offers with manufacturing companies after completing the free registration process and joining our online marketplace. This helps to ensure that you conclude the pharmaceutical product deal at a reasonable cost and achieve the best cost/benefit ratio for your company while bypassing lengthy sourcing, negotiation, and order process. Once you have finalized a deal, you can look forward to a long-lasting business relationship with the manufacturers Nebivolol suppliers. This way, the marketplace allows you as a distributor to skip the process of shortlisting product manufacturers every time you are looking for in-licensing or distribution deals.
To keep up to the quality standards other than Good Manufacturing Practice approvals that this medicine manufacturers list has, we qualify their companies before they are onboarded on the platform. This allows us to screen Nebivolol for the quality of the pharmaceutical products’ dossiers and protect against the risk of possible malpractices.