Methylprednisolone Sodium Succinate Manufacturers

Methylprednisolone sodium succinate is a corticosteroid medication that is useful in reducing inflammation. WhichMainly leads to a reduction in pain and improvement of a variety of symptoms associated with injury, inflammation, and allergy. This drug is marketed with the Brand Name SOLU-MEDROL. Methylprednisolone sodium succinate is used for emergency or acute type conditions where a rapid response is required. The main uses of methylprednisolone sodium succinate include the Severe allergic reactions– Methylprednisolone sodium succinate should be given after immediate treatment with adrenaline or an Epipen. Status asthmaticus (severe asthma attacks)- Although methylprednisolone sodium succinate does not act immediately it should still be given in the event of an acute attack. Suppression of transplant rejection. Cerebral edema (swelling due to fluid). Inflammatory bowel disease in severely ill patients. Systemic lupus erythematosus (a multi-system inflammatory disorder). Rheumatic disorders– Useful in acute attacks. Certain types of meningitis and pneumonia are also considered. This medication basically means that it is a steroid medication produced in the center (cortex) of the adrenal gland. Methylprednisolone has a specific ‘glucocorticoid’ effect meaning that it predominantly acts to reduce the body normal inflammation and immune responses which is achieved by modifying the nature of various genes which lies within the tissue cells. Like the other steroids, methylprednisolone also causes mild water and salt retention in the kidneys. However, this effect has far less potency toward it. Methylprednisolone Sodium Succinate is supplied as a dry white powder which is required to dissolve in water before administration. Methylprednisolone is administered either intramuscularly or intravenously. This medication should be administered under the supervision of a medical practitioner or health care professional. Methylprednisolone Sodium Succinate is available in two different dosage strengths 500mg (in a 20mL glass vial) or 1000mg (in a 30mL glass vial). Methylprednisolone Sodium Succinate vials are recommended to be stored at 20° C to 25° C (68° F - 77° F)

Wholesale Price of Methylprednisolone Sodium Succinate

The wholesale price of Methylprednisolone Sodium Succinate injectable powder for injection (1 g preservative-free) is around $72 for a supply of 1 powder for injection, The cost for Methylprednisolone Sodium Succinate injectable powder for injection (40 g preservative-free) is around $ 167.29 for a supply of 25 powder for injection and the per-unit cost comes at as low as $ 6.69.

Methylprednisolone Sodium Succinate - Mechanism of action:

Methylprednisolone binds and activates specific nuclear receptors, which are resulting in altered gene expression by the inhibition of proinflammatory cytokine production. Produced agent also decreases the number of circulating lymphocytes, induces cell differentiation, and stimulates apoptosis in sensitive tumour cell populations. It also acts as in to various ways to decrease the inflammatory cycle including: dampening the inflammatory cytokine inhibits the activation of T cells, which decreases the extravasation of immune cells into the central nervous system which in turn facilitates the apoptosis of activated immune cells, and thereby indirectly decreases the cytotoxic effects of nitric oxide and tumour necrosis.

Finding Methylprednisolone Sodium Succinate Manufacturers and Suppliers

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