Lurbinectedin injection is being used to cure small cell lung cancer (SCLC) that has progressed to other regions of the body that did not respond to platinum chemotherapy during or after treatment. Lurbinectedin injection belongs to the alkylating agent class of drugs. It works by reducing or preventing cancer cell development in the body. Zepzelca is the brand name for it.
How Does Lurbinectedin Work?
Lurbinectedin works by alkylating DNA. It forms adducts with guanine residues in the DNA minor groove, bending the DNA helix more toward the major groove. This mechanism sets off a chain of events that disrupt transcription factor activity and degrade DNA repair pathways, eventually leading to double-strand DNA lesions and cell death. Reduction of RNA-polymerase-II activity, deactivation of Weir Sarcoma Oncoprotein (EWS-FL11) through nuclear translocation, and reduction of human monocyte interaction and macrophage infiltration into tumor tissue are all additional modes of action.
This injection is a powder that is combined with liquid and given intravenously (into a vein) by a doctor or nurse in a hospital or medical center over a 1 hour period. It is typically administered once every 21 days.
The Wholesale Price of Lurbinectedin
Based on the pharmacy you visit, the cost of Lurbinectedin (Zepzelca) intravenous powder for injection 4 mg for a supply of 1 powder for injection is roughly $7,211. Prices are only applicable for cash-paying consumers and do not apply to insurance schemes. Despite the fact that local prices are believed to be much lower than those in the United States, the patient pool that may be able to pay for the therapy is being questioned. Pharmaceutical corporations generally support patient assistance programs (PAPs), which provide free or subsidized drugs to low-income, unemployed, or under-insured patients who meet certain criteria.
Navigating our Pharmaceutical Marketplace
Being a global B2B pharmaceutical online marketplace, Pipelinepharma is structured to simplify pharmaceutical deals by providing you with an intuitive interface that is easy to engage with. The selection of Lurbinectedin offerings can be narrowed down with the use of filters and easily weighed against one another according to medication prices and commercial terms. The advanced filters help you filter out the countries for these substance manufacturers and these substance suppliers that you are looking for. These also enable you to check the dossier status of this medicine, and the GMP approvals of the different variants of Lurbinectedin. Also, each manufacturer or supplier product description contains essential information about this substance including clinical data, stability zones, countries where Lurbinectedin is already registered in. Manufacturers also have special, and delivery terms.
Establishing Commercial Ties
If you are a pharmaceutical licensing company or a distributor you can enter into deals or negotiations over these medicine offers with manufacturing companies after completing the free registration process and joining our online marketplace. This helps to ensure that you conclude the pharmaceutical deal at a reasonable cost and achieve the best cost/benefit ratio for your company while bypassing lengthy sourcing, negotiation, and ordering process. Once you have finalized a deal, you can look forward to a long-lasting business relationship with the manufacturers or suppliers. This way, the marketplace allows you as a distributor to skip the process of shortlisting product manufacturers every time you are looking for in-licensing or distribution deals.
To keep up to the quality standards other than Good Manufacturing Practice approvals that this medicine manufacturers list has, we qualify their companies before they are boarded on the platform. This allows us to screen Lurbinectedin manufacturers for the quality of the pharmaceutical products’ dossiers and protect against the risk of possible malpractices.