Lisinopril is a medication that belongs to a class of drugs known as angiotensin-converting enzyme (ACE) inhibitors. It is commonly used to treat high blood pressure, heart failure and to improve survival after a heart attack.
Lisinopril works by blocking the activity of ACE, which converts angiotensin I to angiotensin II. By blocking the activity of ACE, Lisinopril helps to relax blood vessels, lower blood pressure, and reduce the workload on the heart.
Lisinopril is taken orally, usually once daily, with or without food.
As with all medications, Lisinopril may cause side effects, including dizziness, headache, cough, fatigue, and gastrointestinal upset. In rare cases, it may also cause more serious side effects such as kidney problems, allergic reactions, or low blood pressure.
Lisinopril is available in different forms and dosages. The most common form is an oral tablet, but it can also be found in other formulations, such as oral solution.
Lisinopril tablets come in various strengths, including 2.5mg, 5mg, 10mg, 20mg, 30mg, and 40mg. The recommended dosage of Lisinopril depends on the condition being treated and other factors such as age, weight, and overall health. The usual starting dose for high blood pressure is 10mg once daily, and the maximum dose is typically 40mg per day.
The starting dose for heart failure is usually 2.5-5 mg once daily, which may be increased gradually over time to a maximum dose of 40mg daily. For patients with a recent heart attack, the starting dose is usually 5mg once daily, which may be increased to 10mg after several days.
Lisinopril oral solution is available in a concentration of 1mg/mL. The recommended dosage of the oral solution is usually the same as for the tablet form, but it may be adjusted based on individual needs and the instructions of the prescribing healthcare provider.
The patent for Lisinopril has expired, and the drug is now widely available as a generic medication. The original patent for Lisinopril was held by Merck & Co., Inc., and it was first filed in 1980. The patent was granted in 1984 and expired in 2001.
Generic Lisinopril is sold under a variety of brand names and is available in various strengths and formulations.
In the United States, Lisinopril tablet costs vary on the final dosage form:
In the United Kingdom, Lisinopril NHS cost was about ₤10 per month in 2018.
In France, Lisinopril 20 mg price is around 4.5 EUR per 28-tablet pack.
Lisinopril is a globally found drug under generic and trade names. The most known brand name for Lisinopril is Zestril by Merck, but as the patent expired in 2002, many manufacturers have started producing their products.
Among these Lisinopril brand names, we can list Acebitor by GlaxoSmithKline, Acerbon by AstraZeneca, Acinopril and Fosinopril by Sanofi-Aventis, Bellisin by Ranbaxy, Biopril by Biochem, Dapril by Medochemie, Fibsol by Sigma, Hipril by Micro Labs, Presiten by Magnachem, Ranolip and Sinopren by Ranbaxy, Rantex by Biotech, Tensopril by Merck.
Lisinopril is produced by different manufacturers, such as Actavis Elizabeth Llc, Apotex Inc Etobicoke Site, Aurobindo Pharma Ltd, Lupin Ltd, Mylan Pharmaceuticals Inc, Ranbaxy Pharmaceuticals Inc, Sandoz Inc, Teva Pharmaceuticals USA Inc, Vintage Pharmaceuticals Llc, Watson Laboratories Inc.
Pipelinepharma is a B2B online marketplace that can help pharma buyers source Lisinopril thanks to:
More than 100 Lisinopril products are in the Pipelinepharma marketplace, listed in the Generics category. There are products with EU GMP approvals and several ready-to-file EU CTD dossiers.
In addition to tablets, buyers can submit business inquiries for the oral solution of Lisinopril.