Levofloxacin HCl, a hydrochloride salt form of Levofloxacin is a broad-spectrum fluoroquinolone
antibiotic. It is also an optical S-(-) isomer of Ofloxacin. The compound is a DNA gyrase inhibitor
that inhibits topoisomerase IV. It treats a wide range of infections including Nosocomial
Pneumonia, Community-Acquired Pneumonia, Complicated and uncomplicated Skin, and Skin
Structure Infections, Uncomplicated Skin, and Skin Structure Infections, Chronic Bacterial
Prostatitis, Inhalational Anthrax (Post-Exposure), Plague, Complicated & uncomplicated Urinary
Tract Infections, Acute Pyelonephritis, Acute Bacterial Exacerbation of Chronic Bronchitis, Acute
Bacterial Sinusitis among others.
Levofloxacin is sold under the brand names Levaquin, Tavanic, Iquix among others. There are
very severe adverse side effects associated with these medicines so must be taken only upon
a prescription from a doctor, exactly as indicated, and for not more than 14 days.
Takeda Chemical Industries, Ltd. filed for a patent in 1984, it was later approved for sale in
1996. However, after the expiry of the protection of the initial patent, it is now made as a generic
drug around the world by several manufacturers. It is one of the most commonly prescribed
medicines in the USA and has found a place on WHO’s a list of essential medicines.
Dosage and Administration
Levofloxacin is sold as Tablets in 250 mg, 500 mg, or 750 mg strengths administered orally
every 24 hours. The dosage for Nosocomial Pneumonia is 750 mg, take once a day for 7 to 14
days. For Community-Acquired Pneumonia, the dose is500 mg – 750mg, taken for 5 or 7 to 14
course, based on the type. For Complicated Skin and Skin Structure Infections, the dose is 750
mg, taken once a day for 7 to 14 days. For Uncomplicated, the dose is 500 mg for 7 to 10 days.
for Chronic Bacterial Prostatitis, the dose is 500 mg taken for 28 days. for treating Inhalational
Anthrax, Post-Exposure, adult and pediatric patients weighing 50 kg or greater, are given 500
mg for 60 days. for Plague, adult, and pediatric patients weighing 50 kg or greater, the dose is
500 mg, for 10 to 14 days, and for Pediatric patients weighing 30 kg to less than 50 kg, consult
the doctor. For treating Complicated Urinary Tract Infection or Acute Pyelonephritis, the dose is
750 mg taken for 5 days.
The price of Levofloxacin
In the USA, The consumer has to pay an average cost of $168.99 for 10 Tablets of 500mg
each. The same supply of 10 tablets of 500mg costs USD 10 in India.
How does it work?
Levofloxacin exerts its actions like other fluoroquinolone antimicrobials. It gets involved in
inhibiting bacterial topoisomerase IV and DNA gyrase, both of which are type II topoisomerases
and are enzymes required for DNA replication, transcription, repair, and recombination. By
inhibiting those, the medicine is able to result in the death of bacteria.
Finding Levofloxacin HCL Manufacturers and Suppliers:
The process of finding trusted Levofloxacin HCL manufacturers and Levofloxacin HCL suppliers
can be made quicker and more accessible by using Pipelinepharma's online platform, a B2B
a marketplace that lets you finalize the deals of pharmaceutical products in a matter of a few
clicks. In addition, it is an easy-to-use online platform to grow your business opportunities.
The robust search engine makes it convenient to search for manufacturers and suppliers of
Levofloxacin HCL. The search can be further refined with industry-specific filters such as
dossier type, country of origin, GMP approvals, and search criteria for Wholesaler, etc. helping
to get in contact with the preferred manufacturer and supplier readily.