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imatinib mesylate

Tablets 0.1 g

Dossier type
CTD
Dossier status
Ready to file
Country of origin
China
GMP approvals
China
Manufacturer #31064

Established in 1970, this Chinese manufacturer specializes in the research, development, production, and sales of a wide range of pharmaceutical products. As a CTD dossier owner and manufacturer, it ensures compliance with international quality standards. The company operates advanced production lines across four industrial parks, covering approximately 1,333,400 square meters, and employs nearly 5,000 individuals, including over 2,000 professional and technical personnel. Its diverse product portfolio includes anesthetic agents, psychotropic medicines, nonsteroidal anti-inflammatory drugs, cardiovascular system medicines, antibiotics, and antiviral medicines. As a CTD dossier owner and manufacturer, its products are distributed across multiple countries worldwide. The manufacturer holds GMP certifications from international regulatory authorities, including the U.S. FDA and the Philippines FDA, ensuring adherence to stringent global quality standards

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Imatinib Mesylate

Imatinib Mesylate is used to treat certain types of leukaemia, type of cancers that begins in the white blood cells, other cancers and disorders of the blood cells. Imatinib is also used to treat certain types of gastrointestinal stromal tumours, a type of tumour that grows in the walls of the digestive passages and may spread to other parts of the body. Imatinib is also used to treat tumours that forms under the top layer of skin, especially when the tumour cannot be removed surgically, has spread to other parts of the body, or has come back after surgery. Imatinib is in a class of medications called kinase inhibitors. It works by blocking the action of the abnormal protein that signals cancer cells to multiply. This helps stop the spread of cancer cells.
Imatinib is sold under the brand name Gleevec among others.
Scientists at Ciba-Geigy (which merged with Sandoz in 1996 to become Novartis) invented Imatinib in the late 1990s, in a team led by biochemist Nicholas Lydon and that included Elisabeth Buchdunger and Jürg Zimmermann.

Forms and Dosage

It is sold in the tablet form in 100mg, 400mg strengths, in the treatment of Acute Lymphoblastic Leukaemia, the Indicated dosage for adults is 600 mg per day. In the treatment of Myelodysplastic/Myeloproliferative Diseases, the standard adult dose is 400 mg. in the treatment of Chronic Eosinophilic Leukemia, 100 mg which may increase to 400 mg. for treating Mastocytosis, the Indicated dosage for adults with aggressive systemic mastocytosis is 400 mg PO qDay and for Gastrointestinal Stromal Tumors, 400 mg

The cost of Imatinib Mesylate

The wholesale cost in the developing world is about US$1,386.49–19,162.50 a year. Whereas In the United States a typical dose for a year has a wholesale cost of $84,408, while in the United Kingdom the NHS was paying about £20,980 ($27,973) in 2016. Prices for a 100 mg pill of Gleevec internationally range from $20 to $30, although generic Imatinib is cheaper, as low as $2 per pill.

How does Imatinib Mesylatework?

Imatinib is a cancer growth blocker called a tyrosine kinase inhibitor. These inhibitors are proteins that cells use to signal to each other to grow. There are a number of different tyrosine kinases and blocking them stops the cancer cells growing. Imatinib targets different tyrosine kinases, depending on the type of cancer.

Finding Imatinib Manufacturers and Suppliers

The process of finding trusted Imatinib manufacturers and Imatinib suppliers can be made quicker and more accessible by using Pipelinepharma's online platform, a B2B marketplace that lets you finalize the deals of pharmaceutical products in a matter of a few clicks. Also, it is an easy to use online platform to grow your business opportunities.
The robust search engine makes it convenient to search for manufacturers and suppliers of Imatinib . The search can be further refined with industry-specific filters such as dossier type, country of origin, GMP approvals, and search criteria for Wholesaler, etc. helping to get in contact with the preferred manufacturer and supplier readily.

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