Hyaluronic acid manufacturers

What is Hyaluronic acid?

Hyaluronic acid (HA) is a naturally occurring sugar molecule found in the body. It is a key component of connective tissue, such as skin and cartilage, and plays an important role in tissue repair and hydration. Hyaluronic acid has a range of functions that make it a popular ingredient in skincare and medical treatments.

HA is a glycosaminoglycan - a molecule composed of repeating units of sugars and amino acids. It is highly hydrophilic, attracting and retaining water, making it an essential part of the skin's natural moisture barrier.

In the skincare and beauty industry, hyaluronic acid is often used in topical products such as serums and moisturizers due to its ability to hydrate and plump the skin. It can also be used in injectable forms for cosmetic treatments, such as dermal fillers, to add volume to the skin and reduce the appearance of wrinkles.

Hyaluronic acid has also been used in medical treatments for joint pain and inflammation and in eye surgeries to replace natural fluids in the eye.

Hyaluronic acid and Hyaluronic acid Sodium

Hyaluronic acid and Hyaluronic acid sodium are not exactly the same products, but they are closely related.

Hyaluronic acid is a molecule naturally found in connective tissue and skin. When used in skincare, Hyaluronic acid is typically derived from bacterial fermentation, animal sources, or synthesized in a laboratory.

Hyaluronic acid Sodium is the salt form of hyaluronic acid. It is created by adding Sodium hydroxide to Hyaluronic acid, which results in a more stable and water-soluble form. This form of Hyaluronic acid is commonly used in topical skincare products, such as serums and moisturizers.

So, while Hyaluronic acid and Hyaluronic acid Sodium are not the same, they are closely related and often used interchangeably in skincare products. Both forms of hyaluronic acid are effective at hydrating and plumping the skin. However, Hyaluronic acid Sodium is often preferred in skincare formulations due to its stability and solubility in water.

Hyaluronic acid's primary use cases in medicine

Some of the medical applications of Hyaluronic acid include:

1. Ophthalmology: Hyaluronic acid is used in ophthalmology to treat dry eyes, corneal ulcers, and other ocular conditions. It can be used as an artificial tear to lubricate the eye's surface and as a surgical aid during cataracts and other eye surgeries.
2. Orthopedics: Hyaluronic acid injections are used to treat osteoarthritis and other joint disorders. The injections can reduce pain and inflammation and improve joint mobility by providing cushioning and lubrication to the affected joint.
3. Dermatology: Hyaluronic acid is used in dermal fillers to minimize wrinkles and fine lines. The injections can restore volume to the skin and improve its texture and elasticity.
4. Wound healing: Hyaluronic acid is used in wound dressings to promote healing and reduce scarring. It can help create a moist environment that facilitates healing and provides a barrier against infection.
5. Cancer treatment: Hyaluronic acid is being investigated as a potential drug delivery vehicle for treating cancer. The molecule can selectively accumulate in tumour tissues and release drugs locally, reducing the side effects associated with traditional chemotherapy.

Overall, hyaluronic acid has several medical uses and is considered to be safe and well-tolerated by most patients.

Hyaluronic acid's form and dosage

Hyaluronic acid (HA) is available in several forms, depending on its intended use. Some common forms of HA and their dosages include:

• Injectable hyaluronic acid: This form of HA is used in dermal fillers to reduce the appearance of wrinkles and fine lines. The dosage and number of injections needed can vary depending on the area being treated and the severity of the wrinkles. Typically, treatments are done every 6 to 12 months.
• Topical hyaluronic acid: This form of HA is used in skincare products such as moisturizers and serums. The concentration and dosage of HA can vary depending on the product but typically ranges from 0.1% to 2%. It is applied to the skin once or twice a day, depending on the product instructions.
• Oral hyaluronic acid: This form of HA is available in supplement form and is taken orally. The dosage can vary depending on the product but typically ranges from 20 to 200 mg per day. It is commonly used to improve joint health and reduce joint pain.
• Hyaluronic acid eye drops: This form of HA is used in eye drops to treat dry eyes and other ocular conditions. The dosage and frequency of use can vary depending on the product and the severity of the condition.

Hyaluronic acid's patent information

Hyaluronic acid (HA) was first identified in the 1930s and has been widely studied for its medical applications. As a natural molecule found in the body, HA itself cannot be patented. However, there are several patents related to the use of HA in medical and cosmetic applications.

For example, numerous patents are related to using HA in dermal fillers for cosmetic purposes, such as reducing wrinkles and fine lines. These patents cover specific formulations of HA, injection techniques, and manufacturing processes for HA-based fillers.

There are also patents related to the use of HA in pharmaceuticals, such as for the treatment of osteoarthritis and other joint disorders. These patents cover specific formulations and dosages of HA for therapeutic use.

Overall, the patent landscape for HA is complex and dynamic, with numerous patents covering different aspects of its use in medicine and cosmetics.

Hyaluronic acid's wholesale price

In general, the cost of Hyaluronic acid (HA) tends to be higher for medical-grade or pharmaceutical-grade products compared to cosmetic-grade products.

For injectable HA used in dermal fillers, the wholesale price can range from $100 to $500 per ml, depending on the brand and quality of the product.

For topical HA used in skincare products, the wholesale price can range from $50 to $200 per kg, depending on the concentration and quality of the product.

For oral supplements, the wholesale price of HA can range from $200 to $500 per kg, depending on the dosage and quality of the product.

Hyaluronic acid's manufacturers and brands

There are many manufacturers and brands of Hyaluronic acid products worldwide. In addition to skincare, many Hyaluronic acid products are registered as medical devices. Here are some companies that manufacture hyaluronic acid as a medical device:

1. Fidia Farmaceutici S.p.A. (Italy) - Fidia produces hyaluronic acid-based products for orthopaedic applications, such as osteoarthritis and joint pain, under the brand name Hyalgan.
2. Anika Therapeutics, Inc. (USA) - Anika produces hyaluronic acid-based products for various medical and aesthetic applications, such as dermal fillers and wound care, under the brand names Hyalofast and Hyvisc.
3. Galderma SA (Switzerland) - Galderma produces hyaluronic acid-based dermal fillers for cosmetic use, such as Restylane and Emervel.
4. Zimmer Biomet (USA) - Zimmer Biomet produces hyaluronic acid-based products for orthopaedic applications, such as Synvisc-One for knee osteoarthritis.
5. Ferring Pharmaceuticals (Switzerland) - Ferring produces hyaluronic acid-based products for urological applications, such as Deflux for vesicoureteral reflux.

Connecting to Hyaluronic acid's manufacturers and suppliers

On the Pipelinepharma platform, B2B pharma buyers can find a wide range of products, including Hyaluronic acid-based products, from various manufacturers and suppliers. The platform offers a user-friendly interface allowing buyers to search and filter products based on multiple criteria, such as product type, therapy area, country of origin, etc.

If you are a B2B pharma buyer interested in sourcing Hyaluronic acid products on Pipelinepharma, visit the platform's website and create a free account to browse the available products, submit business inquiries and connect with suppliers.

More than 200 Hyaluronic acid products are in the Pipelinepharma marketplace, mainly listed across Medical devices and Nutraceutical categories.