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Fasudil manufacturers

1 products found

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1 products found

fasudil

Solution for injection 30 mg - 2 ml

Dossier type
CTD
Dossier status
Ready to file
Country of origin
China
GMP approvals
China
Manufacturer #12677

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Fasudil is a potent Rho-kinase inhibitor and vasodilator. It is widely prescribed for the treatment of cerebral vasospasm often caused by a subarachnoid hemorrhage. It helps improve cognitive decline in patients of stroke. Moreover, It has also been effectively used for the treatment of pulmonary hypertension and a promising drug for a new therapy of amyotrophic lateral sclerosis. It is sold as Chuanwei made by Chase Sun Pharmaceutical in china and as Eril by Asahi Kasei Pharma, in Japan. It has been approved for sale in Japan and China, but is yet to be approved by the United States Food and Drug Administration or by the European Medicines Agency. Dosage: Fasudil is sold as 30 mg tablets can be dissolved in 20 mL of saline and 15–45 cc of this solution can be infused through a microcatheter at a rate of 1–2 cc/min. a higher dosage has been associated with serveral complications. Cost of Fasudil A vial containing 30mg in a 2ml vial costs around usd50 in countries where it has been approved for sale. How does it work? Fasudil is a selective RhoA/Rho kinase (ROCK) inhibitor. This inhibitor is an enzyme that plays an important role in mediating vasoconstriction and vascular remodeling in the pulmonary hypertension. ROCK causes vasoconstriction by binding subunit of myosin light chain phosphatase, thus decreasing phosphatase activity which causes the problem and enhancing vascular smooth muscle contraction. Finding Fasudil Manufacturers and Suppliers: The process of finding trusted Fasudil manufacturers and Fasudil suppliers can be made quicker and more accessible by using Pipelinepharma's online platform, a B2B marketplace that lets you finalize the deals of pharmaceutical products in a matter of a few clicks. Also, it is an easy to use online platform to grow your business opportunities. The robust search engine makes it convenient to search for manufacturers and suppliers of Fasudil. The search can be further refined with industry-specific filters such as dossier type, country of origin, GMP approvals, and search criteria for Wholesaler, etc. helping to get in contact with the preferred manufacturer and supplier readily.

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