Etoposide is a chemotherapy medication used to treat testicular, lung, ovarian cancer, as well as lymphoma, leukemia, and neuroblastoma. Etoposide belongs to a group of drugs called podophyllotoxin derivatives. It functions by reducing or halting the development of cancer cells within the body. Manufacturers and suppliers of etoposide typically market it as 20mg/ml concentrate for an intravenous solution, although it is also available in capsule form. The drug was first approved for medical use in 1983, with the earliest manufacturer being Bristol-Myers Squibb. Currently, etoposide is on the WHO’s list of Essential Medicines and, with the supplier’s patent having had expired, other manufacturers and vendors have since joined the global market for the drug. Among the largest etoposide manufacturers and suppliers are well-known pharmaceutical companies Pharmedic Laboratories, Teva, Sandoz, Accord Healthcare, and Fresenius Kabi.
How Does Etoposide Work?
It acts by reducing or halting the development of cancer cells within the body. DNA re-ligation is prevented by etoposide's inhibition of DNA topoisomerase II. This results in significant mistakes in DNA synthesis during the premitotic stage of cell division, which may cause the cancer cell to undergo apoptosis. Etoposide primarily affects the S and G2 phases of cell division and is cell cycle sensitive and phase specific. Etoposide develops anti-tumor action when topoisomerase II alpha isoform is inhibited. Although the medication has the potential to block the beta isoform as well, this target's suppression is unrelated to the anti-tumor effect. Instead, it is linked to the cancer-causing impact. The assembly of microtubules is unaffected. Either the production of free radicals or the production of DNA strand breaks through a contact with DNA-topoisomerase II seem to be the main macromolecular effects of etoposide.
Wholesale Price of Etoposide
The retail prices per 5ml of 20mg/ml concentrate for injectable solution fall into an approximate range of 7,00 EUR to 12,00 EUR. The costs of Etoposide vary depending on manufacturer and supplier pricing, whether it is a generic or trade name formulation, concentration of the active ingredient in the formulation. It is available or sale at every medical store. Etoposide suppliers, on the whole, are in favor of patient aid schemes. Etoposide is available for sale from various Etoposide vendors at multiple costs. Explore the offers of Etoposide from vendors on our pharmaceutical marketplace or to look up more essential online information about Etoposide.
From Where to Get Etoposide?
Etoposide suppliers and distributors market both generic and trade name formulations of the drug. Pharmaceutical specialists are welcome to browse through offers of Etoposide in our B2B pharmaceutical marketplace, or else find more information about Etoposide online. Finding reliable suppliers and manufacturers of particular medications like Etoposide can typically be a time-consuming challenge, but with Pipelinepharma's straightforward search engine and network of tested partners, the entire process becomes much simpler. Making use of Pipelinepharma's worldwide B2B online marketplace for medications and other pharmaceuticals is the ideal approach to locate and acquire access to Etoposide manufacturers and suppliers. Utilizing our built-in search engine, all you have to do to begin going is start looking for potential Etoposide suppliers or manufacturers. You may also use filters to narrow down your search results and look for Etoposide from particular nations.
Navigating our Pharmaceutical Marketplace
Being a global B2B pharmaceutical online marketplace, Pipelinepharma is structured to simplify pharmaceutical deals by providing you with an intuitive interface that is easy to engage with. The selection of Etoposide offerings can be narrowed down with filters and easily weighed against one another according to medication prices and commercial terms. The advanced filters help you filter out the countries for this substance manufacturer and Etoposide suppliers that you are looking for. These also enable you to check the dossier status of this medicine and the GMP approvals of the different variants of Etoposide. Also, each manufacturer or supplier product description contains essential information about this substance, including clinical data, stability zones, and countries in which Etoposide is already registered. Manufacturers also have special delivery terms.
Establishing Commercial Ties
Suppose you are a pharmaceutical licensing company or a distributor. In that case, you can enter into deals or negotiations over these medicine offers with manufacturing companies after completing the free registration process and joining our online marketplace. This helps ensure that you conclude the pharmaceutical deal at a reasonable cost and achieve the best cost/benefit ratio for your company while bypassing lengthy sourcing, negotiation, and order process. Once you have finalized a deal, you can look forward to a long-lasting business relationship with the Etoposide suppliers. This way, the marketplace allows you as a distributor to skip the process of making a list of product manufacturers every time you are looking for in-licensing or distribution deals.
To keep up to the quality standards other than Good Manufacturing Practice approvals that this medicine manufacturers list has, we qualify their companies before they are boarded on the platform. This allows us to screen Etoposide manufacturers for the quality of the pharmaceutical products' dossiers and protect against the risk of possible malpractices.