Erlotinib is a medication used to treat non-small cell lung cancer and pancreatic cancer. Erlotinib suppliers and distributors market the drug in the form of 25mg, 100mg, 150mg oral tablets. The developer and earliest erlotinib manufacturer was Roche, who first acquired approval to market the drug in 2004. Currently, the medication is available in over 50 countries worldwide and is included on the World Health Organisation’s list of Essential Medicines that contains the safest and most effective drugs recommended for a health system. Erlotinib suppliers in the U.S are OSI Pharma and Genentech, whereas across all of the other geographical markets, erlotinib is supplied by Roche. Other major erlotinib manufacturers and suppliers include companies such as Sandoz and Teva. Given that the patent of Roche has since expired, erlotinib suppliers and distributors market both generic and trade name formulations of the drug.
How Does Erlotinib Work?
Erlotinib's clinical antitumor action's method is not completely understood. The phosphorylation of tyrosine kinase linked to the epidermal growth factor receptor intracellularly is inhibited by erlotinib (EGFR). It has not yet been thoroughly described how specifically other tyrosine kinase receptors are inhibited. Both healthy cells and malignant cells express the EGFR protein on their cell surfaces. After being taken orally, erlotinib is only around 60% absorbed, but eating increases its bioavailability to almost 100%. Four hours after medication, peak plasma levels happen. Erlotinib's solubility is pH-dependent. pH rises as solubility falls. Erlotinib exposure is also decreased by smoking. In the liver, metabolism takes place. Erlotinib is largely metabolised by CYP3A4 and to a lesser amount by CYP1A2, as well as the extrahepatic isoform of CYP1A1, according to in vitro tests of cytochrome P450 metabolism.
Wholesale Price of Erlotinib
Costs of erlotinib vary depending on manufacturer and supplier pricing, whether it is a generic or trade name formulation, concentration of the active ingredient in the formulation. The retail prices per 30 (100mg) tablets of erlotinib fall into an approximate range of 650 EUR to 1000 EUR, whereas the equivalent amount of 150mg tablets can cost anywhere from 900 EUR to 1,300 EUR. Also the costs of Erlotinib vary depending on manufacturer and supplier pricing, whether it is a generic or trade name formulation, concentration of the active ingredient in the formulation. Erlotinib is available for sale from various Erlotinib vendors at multiple costs. Erlotinib suppliers, on the whole, are in favor of patient aid initiatives.
From Where to Get Erlotinib?
Buyers are advised that online sellers may attempt to market fraudulent versions of the generic drug, whereas Pipeline Pharma, through its pre-auditing and quality control procedures ensures that only verified Erlotinib manufacturers and wholesalers enter our online marketplace, offering you a risk-free B2B pharmaceutical sales platform. PipelinePharma is the most reliable source for this medication. Finding an honest partner in our business is one of the significant challenges. To overcome this challenge and make one's life easier when looking for a direct manufacturer and supplier of Erlotinib, one can go to the Pipelinepharma website, which assists buyers in locating dependable manufacturers and suppliers of Erlotinib.
Navigating our Pharmaceutical Marketplace
Being a global B2B pharmaceutical online marketplace, Pipelinepharma is structured to simplify pharmaceutical deals by providing you with an intuitive interface that is easy to engage with. The selection of Erlotinib offerings can be narrowed down with filters and easily weighed against one another according to medication prices and commercial terms. The advanced filters help you filter out the countries for this substance manufacturer and Erlotinib suppliers that you are looking for. These also enable you to check the dossier status of this medicine and the GMP approvals of the different variants of Erlotinib. Also, each manufacturer or supplier product description contains essential information about this substance, including clinical data, stability zones, and countries in which Erlotinib is already registered. Manufacturers also have special delivery terms.
Establishing Commercial Ties
Suppose you are a pharmaceutical licensing company or a distributor. In that case, you can enter into deals or negotiations over these medicine offers with manufacturing companies after completing the free registration process and joining our online marketplace. This helps ensure that you conclude the pharmaceutical deal at a reasonable cost and achieve the best cost/benefit ratio for your company while bypassing lengthy sourcing, negotiation, and order process. Once you have finalized a deal, you can look forward to a long-lasting business relationship with the Erlotinib suppliers. This way, the marketplace allows you as a distributor to skip the process of making a list of product manufacturers every time you are looking for in-licensing or distribution deals.
To keep up to the quality standards other than Good Manufacturing Practice approvals that this medicine manufacturers list has, we qualify their companies before they are boarded on the platform. This allows us to screen Erlotinib manufacturers for the quality of the pharmaceutical products' dossiers and protect against the risk of possible malpractices.