Diclofenac Sodium
Diclofenac Sodium, a benzene acetic Acid derivative and nonsteroidal antiinflammatory drug (NSAID), is the sodium salt version of diclofenac. It has analgesic and antipyretic properties and anti-inflammatory activities.
Chronic pain due to cancer is commonly treated with diclofenac, particularly if there is inflammation. If necessary, it can be combined with opioids such as codeine and diclofenac.
It can be used to treat inflammatory disorders, such as arthritis, polymyositis and rheumatoid, polymyositis and osteoarthritis. Acute migraines can also be treated.
How does Diclofenac Sodium work?
It is a competitive and non-selective inhibitor of cyclooxygenase COX, thereby blocking conversion of arachidonic acids into prostaglandin precursors. This results in an inhibition of prostaglandin formation that is involved in pain, inflammation, and fever.
It is commonly used to treat mild to moderate postoperative pain. It can also be used to treat actinic Keratosis and minor strains, sprains and contusions (bruises) that cause acute pain.
Diclofenac Sodium was first patented by Ciba-Geigy in 1965. In the United States, it became medically useful in 1988. It can be purchased as a generic drug. It was the 72nd most prescribed medication in America, with over 11 million prescriptions. It can be purchased as either a sodium salt or a potassium salt.
Common side effects include nausea, dizziness or headaches. Severe side effects could include heart disease.stroke.kidney problems,and stomach ulceration. The use of the product is not advised during the third trimester in pregnancy. It is advised to stop using NSAIDs for pregnant women after 20 weeks.
Pricing of Diclofenac Sodium
For a 30 tablet supply, diclofenac oral delayed-release tablet sodium 75 mg costs around $14. Voltaren is a brand name for the drug, which is also sold under other names such as Cataflam, Cambiae, Zorvolex, Zipsor Voltaren-XR and Dyloject.
Sourcing Diclofenac Sodium
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