CLINDAMYCIN PHOSPHATE

Clindamycin Phosphate is a lincomycin antibiotic. It is used to treat "Acne vulgaris", which is a common to form of acne, consisting of non-inflammatory and mildly inflammatory lesions. Its actions stop the growth of bacteria and help reduce the number of acne lesions. In the severe form of acne, the individual suffers from painful nodules. While Acne is not a serious health issue, it can lead to disfiguring, permanent scarring. It can be very upsetting for people who suffer from the disorder. In the United States alone, more than 17 million people have acne. Clindamycin Phosphate is sold under the brand names Cleocin T,clinda –Derm amongst others. Upjohn and co, first filed for a Clindamycin Phosphate patent in1966, and It was first approved for use in 1968. Bayer and Dupont also filed two different patents during the 80s.

Forms and dose:

Clindamycin Phosphate is available as a lotion, medicated pad, swab, or a foam. To administer the lotion, a thin layer of medication usually applied, twice a day. To use the lotion, the patients are asked to shake the bottle well. To treat using a medicated pad or swab, apply to the affected area gently. More than one pad or swab is used depending on the size of the area to be treated. When using the foam, apply once daily to cover the entire affected area. Careful not spray directly onto your hands or face because the foam will begin to melt on contact with warm skin. The foam may be sprayed directly into the cap or onto a cool surface such as a countertop.

The price of Clindamycin Phosphate:

In the USA, the consumer pays an average retail price of $79.08 for a supply of 30 capsules of 300mg. whereas, in India, Clindamycin Phosphate Gel, weighing 15 grams cost $1.8.

How does it work?

Clindamycin slows and stops the growth of bacteria, decreasing swelling. It kills bacteria by inhibiting protein synthesis at the site of protein synthesis. While clindamycin phosphate is inactive in vitro, rapid in vitro hydrolysis can convert it to clindamycin with antibacterial activity. Clindamycin inhibits bacterial protein synthesis at the ribosomal level by binding to the 50S ribosomal subunit, this affects the process of peptide chain initiation.

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