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Caspofungin manufacturers

21 products found

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21 products found

caspofungin

Injection, lyophilized 50 mg, 70 mg

Dossier type
EU CTD
Dossier status
Ready to file
Country of origin
European Union
GMP approvals
EU GMP, Greece
Unavailable markets
Austria , Belgium , Bulgaria , Croatia , Cyprus , Czech Republic , Denmark , Estonia , Finland , France , Germany , Greece , Hungary , Iceland , Ireland , Italy , Kosovo , Latvia , Lithuania , Malta , Netherlands , Norway , Poland , Portugal , Romania , Slovakia , Spain , Sweden , United Kingdom , Vietnam
Available for
Distribution only
Comments
Product is not available for Europe
Manufacturer #298
This company is a global pharmaceutical and commercial organization that has been operating for over five decades. It specializes in injectable and prescription drug products, medical devices, and food supplements. Their manufacturing facilities are EU and US GMP approved. They have a strong presence in international markets, especially in Europe, North America, and Asia. The company also prides itself on its commitment to research and development of new products, particularly in the field of monoclonal antibodies. This commitment has earned them recognition and awards for their innovation and manufacturing excellence.

Manufacturer usually replies in 5 days

caspofungin

Powder for solution for infusion 50 mg, 70 mg

Dossier type
EU CTD
Dossier status
Ready to file
Country of origin
European Union
GMP approvals
EU GMP, FDA
Manufacturer #17457
In the past fifty years, the company has reached significant milestones—a result of enviable performance, strict adherence to the highest ethical and operational standards, and full compliance with global regulatory authorities. During this journey, they have emerged as one of the leading in-house development partners based in Europe, specializing in the development, registration, manufacturing, and life-cycle management of highly complex pharmaceutical technologies and generic formulations.

Manufacturer usually replies in 14 days

caspofungin

Powder for solution for infusion 50 mg, 70 mg

Dossier type
EU CTD
Dossier status
Ready to file
Country of origin
European Union
GMP approvals
FDA, EU GMP, ANVISA
Unavailable markets
Vietnam
Manufacturer #313

A pharmaceutical manufacturer based in the EU that has been active in 50+ countries selling its products in Europe, North America, LATAM, and Asia for 10+ years. Key production lines are Rx, OTC, and nutraceuticals. Main therapeutic areas include the respiratory system, dermatology, and cardiovascular system. The company possesses several branches in LATAM

Manufacturer usually replies in 11 days

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Caspofungin

Caspofungin is a lipopeptide antifungal medication. It is from a new class of antifungals called the echinocandins. It is used to treat yeast lead infections in the blood, stomach, lungs, and oesophagus and some other fungal infections that could not be cured by other medication. It is also the preferred medicine to treat fungal infections in people, whose bodies have a weaker ability to fight the fungus. It has been effective in the treatment of fungal infections caused by Aspergillus and Candida species. Caspofungin is an echinocandin, a new class of antifungal agents with a broad spectrum of activity against all Candida species. It has also been found that amongst 36% those patients who did not respond to other therapies have responded well to Caspofungin therapy, and it was acceptable to 70% of patients whose bodies did not accept or respond to first-line therapies.
Caspofungin is traded globally under the brand name Cancidas amongst others.
James Balkovec, Regina Black and Frances A. Bouffard from Merck & Co., Inc. discovered Caspofungin. Caspofungin acetate in the injection form was originally approved by both USFDA, and the EMEA, in Europe, in 2001. Caspofungin was the first inhibitor of fungal (1→3)-β-D-glucan synthesis to be approved by the USFDA.

Forms and Dosage

Caspofungin is sold as power for injection in 50mg and 70mg per vial. In treatment of Candida Infections, the patient is started off on a dose of 70mg IV infused over an hour. While in the treatment of Esophageal Candidiasis, the Indicated dosage for treatment is 50 mg IV infused over one hour, the medicine is continued for 7-14 days even after the symptom have resolved themselves. In the treatment of Invasive Aspergillosis too the dosage remains the same at 70mg per hour infusion through an IV.

How much does Caspofungin cost?

a single vial for Caspofungin costs $42.4 USD in the USA, whereas it costs 435 pounds in the UK as per the NHS guideline. In India, the same treatment costs USD50 – USD 200 depending on the brand bought

How does Caspofungin work?

Caspofungin works by stopping the growth of the fungi causing the infection. An integral component of the cell wall of fungal species is β(1,3)-D-Glucan. The chains of β(1,3)-D- glucan exist in a solid three-dimensional matrix giving the fungal cell its strength and shape. Caspofungin works by inhibiting the enzyme (1→3)-β-D-glucan synthase and thereby disturbing the integrity of the fungal cell wall eventually leading the death of fungal cells.

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