Canagliflozin is a medication used to treat type 2 diabetes. It is available both as a standalone drug and as a combination drug along with metformin. Suppliers market it as 100mg and 300mg canagliflozin tablets. The drug was developed by Mitsubishi Tanabe Pharma, but its marketing rights were subsequently transferred to manufacturer and supplier Janssen (a division of Johnson & Johnson), who markets it under the trade name Invokana. It was first approved for medical use by the European Medicines Agency in 2011 and by the FDA in 2013. The drug is currently marketed by the supplier in over 40 countries and, in 2016 is reported to have been prescribed to patients approximately 3 million times in the U.S. alone. Canagliflozin belongs to a class of drugs known as SGLT-2 inhibitors that also include ertugliflozin (Steglatro by supplier Merck), dapagliflozin (Farxiga by suppliers AstraZeneca and Bristol-Meyers Squibb), and empagliflozin (Jardiance by suppliers Eli Lilly and Boehringer Ingelheim), which are substitutes to dapagliflozin. Of the four, which are all highly comparable in terms of effectiveness and cost, dapagliflozin is the highest-selling drug. Other manufacturing companies have yet to introduce generic or trade name formulations of canagliflozin medications. Pharmaceutical specialists are welcome to browse through offers of canagliflozin tablets from suppliers on our pharmaceutical marketplace, or else seek out further useful medical information about canagliflozin online, at the official Invokana product website.
How Does Canagliflozin Work?
The kidney's proximal tubules contain the sodium-glucose co-transporter 2 (SGLT2), which reabsorbs filtered sugar from the kidney tubular lumen. The SGLT2 co-transporter is inhibited by canagliflozin. This inhibition lowers the body's ability to reabsorb filtered glucose and lowers the renal threshold for glucose (RTG), which causes more glucose to be excreted in the urine. The body's distribution of this medication is wide. A intravenous infusion dose of canagliflozin in healthy subjects resulted in an average distribution volume of 83.5 L at steady state. O-glucuronidation is the main mode of metabolism for canagliflozin. UGT1A9 and UGT2B4 enzymes glucuronidate it primarily to two inactive O-glucuronide intermediates.
Wholesale Price of Canagliflozin
A prescription of 10 tablets cost $10 for 10 mg. Costs of Canagliflozin vary depending on manufacturer and supplier pricing, whether it is a generic or trade name formulation, concentration of the active ingredient in the formulation. Canagliflozin is available for sale from various Canagliflozin vendors at multiple costs. Prices are applicable just for cash consumers and do not apply to insurance policies. Canagliflozin suppliers, on the whole, are in favor of patient aid initiatives. This cost may differ among dealers.
From Where to Get Canagliflozin?
It is advised to the buyers that online sellers may attempt to market fraudulent versions of the generic drug, whereas Pipeline Pharma, through its pre-auditing and quality control procedures ensures that only verified Canagliflozin manufacturers and wholesalers enter our online marketplace, offering you a risk-free B2B pharmaceutical sales platform. PipelinePharma is the most reliable source for this medication. Finding an honest partner in our business is one of the significant challenges. To overcome this challenge and make one's life easier when looking for a direct manufacturer and supplier of Canagliflozin, one can go to the Pipelinepharma website, which assists buyers in locating dependable manufacturers and suppliers of Canagliflozin.
Navigating our Pharmaceutical Marketplace
Being a global B2B pharmaceutical online marketplace, Pipelinepharma is structured to simplify pharmaceutical deals by providing you with an intuitive interface that is easy to engage with. The selection of Canagliflozin offerings can be narrowed down with filters and easily weighed against one another according to medication prices and commercial terms. The advanced filters help you filter out the countries for this substance manufacturer and Canagliflozin suppliers that you are looking for. These also enable you to check the dossier status of this medicine and the GMP approvals of the different variants of Canagliflozin. Also, each manufacturer or supplier product description contains essential information about this substance, including clinical data, stability zones, and countries in which Canagliflozin is already registered. Manufacturers also have special delivery terms.
Establishing Commercial Ties
Suppose you are a pharmaceutical licensing company or a distributor. In that case, you can enter into deals or negotiations over these medicine offers with manufacturing companies after completing the free registration process and joining our online marketplace. This helps ensure that you conclude the pharmaceutical deal at a reasonable cost and achieve the best cost/benefit ratio for your company while bypassing lengthy sourcing, negotiation, and order process. Once you have finalized a deal, you can look forward to a long-lasting business relationship with the Canagliflozin suppliers. This way, the marketplace allows you as a distributor to skip the process of making a list of product manufacturers every time you are looking for in-licensing or distribution deals.
To keep up to the quality standards other than Good Manufacturing Practice approvals that this medicine manufacturers list has, we qualify their companies before they are boarded on the platform. This allows us to screen Canagliflozin manufacturers for the quality of the pharmaceutical products' dossiers and protect against the risk of possible malpractices.