Lidocaine is a commonly used medication for facilitating local anesthetic that numbs the sensations of tissues in various surgical procedures. This drug is indicated for producing local or regional anesthesia and belongs to a class of drugs called local anesthetics.
This medication is also used topically on the skin to stop pain and itching from certain skin conditions like minor burns, eczema, insect bites, scrapes and to treat discomfort and itching caused by hemorrhoids and certain problems at the anal and genital area.
Lidocaine is used to treat irregular heart rhythms which may lead to a possible risk to the cardiovascular system. Because of this, lidocaine is also considered as anti-arrhythmic agent.
Lidocaine comes as a prescription product, generic prescription product, over the counter products as well as mixture products.
Manufacturers market Lidocaine drug under the Brand name of Astero, AneCream, Bactine, Glydo, Lido Rx. Lidocaine comes as a Gel, Cream, Lotion, Liquid, Ointment, Injection (Solution). There is no pill form of Lidocaine. Gel, Cream, Lotion, Ointment are applied topically and injection is administered through infiltration and intravenous route. Lidocaine is supplied in dosage strengths of 1%, 1.5%, 1.8%, 2%, 4%.
The initial adult dose for ventricular fibrillation is 50 to 100 mg I.V bolus once over 2 to 3 minutes, following bolus administration 1 to 4 mg/min continuous infusion is given. The rate of intravenous infusion should be reevaluated as soon as the cardiac rhythm of the patient appears to be stable.
The maximum individual adult dose for anesthesia is 4 mg/kg given intravenously or 4.5 mg/kg administered through infiltration route. The maximum total dose is 300 mg.
The topical form of lidocaine 1.8% is available as a single dose topical system packaged in an individual envelope. The topical form is applied to the skin to cover the most painful area which is applied as prescribed.
Lidocaine topical systems are stored at 20° C - 25° C (68° F - 77° F) with excursions permitted between 15° C - 30° C (59° F - 86° F)
Lidocaine injectable solutions should be stored at room temperature of 25° C (77° F) and to be protected from light.
Wholesale Price of Lidocaine
The cost for lidocaine intravenous solution 1% is around $ 68 for a supply of 50 milliliters with per unit cost available for a price range of $ 1.36 - $ 1.84 while the cost for 2% intravenous solution is around $ 37 for a supply of 50 milliliters.
The wholesale price of 1.5% Lidocaine injectable solution is around $ 200 for a supply of 500 milliliters and per unit available for a cost of $ 0.40, while the cost for 2 % injectable solution is $ 14 for 50 milliliters with per unit cost available for as low as $ 0.28
Lidocaine - Mechanism of Action
Lidocaine is an amide local anesthetic. It works by blocking nerve signals in the body, exhibits its local anesthetic action by inhibiting the ionic fluxes required for the initiation and conduction of impulses by stabilizing the neuronal membrane.
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