Alendronic Acid Manufacturers
Alendronic acid, often known as Fosamax, is a bisphosphonate medicine that is used to treat osteoporosis and Paget's disease of the bones. It is taken orally. Use is frequently suggested in conjunction with vitamin D supplementation, calcium supplements, and lifestyle changes.
Constipation, stomach pain, vomiting, and acid reflux are common adverse effects that affect 1 to 10% of people. It is not advised to use during pregnancy or if you have impaired renal function. Alendronic acid works by reducing the activity of bone-breaking cells.
Alendronic acid was initially discovered in 1978 and received FDA approval for medical use in 1995. It's a drug that's available as a generic. With over 7 million prescriptions written in 2019, it was the 96th most widely prescribed drug in the United States.
Alendronic acid is a second-generation bisphosphonate that is used to treat osteoporosis and Paget's disease in some cases. It works by keeping bone from resorbing.
Alendronic Acid was prescribed by your doctor to strengthen your bones and reduce the chance of fractures. Take it at least 30 minutes before eating or drinking anything in the morning. To avoid irritating your food pipe, keep an upright posture for 30 minutes after taking the drug. Calcium levels in your blood may drop as a result. Consume calcium-rich foods and undergo regular blood tests to monitor calcium levels in your blood.
After using Alendronic Acid, one should not lie down. This is because the drug has a chance of coming back up into the esophagus (food pipe) and causing harm to the esophagus. Staying upright allows the drug to settle more quickly in your stomach, reducing the risk of side effects such as heartburn and pain.
Hair loss is a possible adverse effect of alendronic acid, however, it is not common. If you notice hair loss while taking this medicine, contact your doctor right away and follow his or her recommendations.
The oral bioavailability of alendronic acid tablets is quite poor. It spreads into soft tissue and bone after ingestion or is eliminated in the urine. Alendronic acid is not broken down by the body.
Skin rashes, including Stevens-Johnson syndrome and toxic epidermal necrolysis, eye issues (uveitis, scleritis), and generalized muscular, joint, and bone pain (rarely severe) have all been documented infrequently. Reduced calcium and phosphate readings may be found in laboratory tests, but they represent the drug's expected activity and are nearly never clinically meaningful.
Long-term usage of alendronate has been linked to the development of low-impact femoral fractures. Furthermore, studies show that alendronate users have more osteoclasts and produce gigantic, multinucleated osteoclasts; nevertheless, the significance of this development is unknown. Fosamax has been related to an uncommon type of leg fracture that occurs with little or no impact and cuts straight across the upper thigh bone (subtrochanteric fractures).
How does Alendronic Acid work?
A bisphosphonate is alendronic acid. It works by inhibiting the activity of osteoclasts, which are cells that break down bone. This helps to strengthen the bones and reduces the chances of fractures.
Alendronic acid boosts calcium levels in your bones (your bone mineral density). Your bones will get stronger and less likely to break as a result of this. After a month, alendronic acid normally begins to function.
Wholesale Price of Alendronic Acid
An online search for the wholesale price for sale of Alendronic Acid for distributors will reveal a wide range of costs. It will vary from store to store depending on your visit and the country of the wholesale market.
Navigating our Pharmaceutical Marketplace
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