It is the successor of one of the largest pharmaceutical manufacturers in southeast Europe. To date, it has been present over 60 years of experience in the development, production, and sale of generic drugs for human and veterinary use. It has a pharmaceutical plant with facilities for the production of the following dosage forms: capsules and tablets, liquid sterile and dry injection forms, semi-solid forms, creams, and ointments for skin and eye use. The plant has the necessary production licenses and certificates of GMP for all productions.
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Travoprost
Travoprost treats high pressure inside the eye including glaucoma, specifically used for open-angle glaucoma when other agents are not sufficient. It is an eye drop which shows effects
generally within two hours. Its actions lower high pressure inside the eye which helps in
preventing blindness. Travoprost regulates the flow of fluid in the eye thus helping to
maintain a normal pressure.
Travoprost is sold under the brand name Travatan among others.
Kabi Pharmacia Ab first file patent or the process to make Travoprost in 1991. It was later
approved for sales in the USA and EU in 2001. In 2017, it was prescribed to more than two
million patients and is now sold as a generic medication in the United Kingdom.
Dosage and administration
Travoprost is sold as a sterile Ophthalmic Solution 0.004%, for Topical Ophthalmic Use.
Travoprost dosage is recommended at one drop in the affected eye once a day in the
evening. It should not be administered more than once a day as frequent administration of
prostaglandin analogs can reduce the intraocular pressure lowering effect. The medicine
starts reducing the intraocular pressure approximately 2 hours after the first administration
and the effect can up to 12 hours. It can also be used concomitantly with other topical
ophthalmic medicines in lowering intraocular pressure. But while being used in combination
with other drugs, they should be administered at least 5 minutes apart.
The price of Travoprost
In the USA, the average retail price of a generic eye dropper with 2.5ml of 0.0004% strength
is sold or around $164.84. In India, the same supply of 2.5ml of one dropper cost around
USD 8.5.
How does Travoprost work?
Travoprost is a synthetic prostaglandin analog or more specifically, an analog of
prostaglandin F2α. Its actions increase the outflow of aqueous fluid from the eyes. Like
other medicines of the same class, like tafluprost and latanoprost, Travoprost is an ester
prodrug of the free acid. These actions make it an agonist at the prostaglandin F receptor.
This helps to increase the outflow of aqueous fluid from the eye. The eventual result of this
the outflow is the lowering of the intraocular pressure.
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