oxaliplatin Solution for injection injection

Dossier type
Dossier status
Under development
Country of origin
United States
Manufacturer #1504

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Oxaliplatin is chemotherapy used to treat advanced cancer of the colon and rectum. It works by slowing or stopping the cancer cells from growing. it is a type of chemotherapy that contains platinum and is administered together with other anticancer drugs, Fluorouracil, and Leucovorin. Oxaliplatin has been found effective against the cancers that have already spread. a three yearlong study of patients treated with Oxaliplatin found that the survival rate amongst the Oxaliplatin-treated patients was 86%, making it one among the simplest drugs of this type. Oxaliplatin is sold under the name Eloxatin amongst others. Professor Yoshinori Kidani of the Nagoya University was granted U.S. Patent in 1979. it had been later in-licensed by Debiopharm and developed into advanced colorectal cancer treatment. Debiopharm then further licensed the drug to Sanofi-Aventis in 1994.

Forms and Dosage

Oxaliplatin is sold as a powder for an injectable solution in 50mg, 100mg, and 200mg vials. within the treatment of colorectal cancer, together with other drugs, the patient is given an initial dose of 85 mg IV infusion to be administered over 120 minutes, every 2 weeks. For the advanced stage of this cancer, the therapy goes on for 12 cycles, spanning 6 months. The recommended dose is repeated every 2 weeks until the disease progresses or reaches levels of unacceptable toxicity. It shouldn't tend to patients with renal impairment or hepatic impairment.

The wholesale price of Oxaliplatin

Currently, consumers can purchase a 50mg supply of this medicine for USD93 within the USA, the worth might be lower thanks to insurance and discounts offered by different pharmacies. the typical price of monthly therapy within the USA is around USD 50. Whereas in India it costs the patient about USD35 for an equivalent supply of Oxaliplatin.

How does Oxaliplatin work?

Oxaliplatin is an alkylating agent, that is most active within the resting phase of the cell. Chemotherapy drugs kill cancer cells only they're dividing, these are called cell-cycle specific. However, Oxaliplatin may be a non-cell-cycle agent, it attacks the cancer cells once they are at rest. The schedule of chemotherapy is targeted towards a specific sort of cells, they specialize in the speed of cellular multiplication, then the acceptable time it selected to administer the therapy for optimum results.

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