A pharmaceutical manufacturer based in the EU that has been active in 60+ countries selling its products in Europe, CIS, and Oceania for 40+ years.
Key production lines are Rx and OTC.
Main therapeutic areas include neurology, cardiology, and infectiology.
The company's production lines are EU GMP-compliant.
The company possesses branches in 10+ countries in Europe and CIS.
Manufacturer usually replies in 8 days
What is Nitrofurantoin
This drug is used to treat or prevent infections of the urinary tract. This drug is an antibiotic that works by preventing germs from growing. It has no effect on viral infections (e.g., common cold, flu).If antibiotics are used excessively or unnecessarily, their efficacy may be lost. This medicine should not be given to children under the age of one month since it can cause a blood issue (hemolytic anemia). Kidney function deteriorates as you age. The kidneys eliminate this medicine. As a result, older persons may be more susceptible to side effects from this medication, particularly nerve, liver, and lung problems. Your urine may turn dark yellow or brown as a result of this drug. This is a mild side effect that will go away once the drug is stopped. The medicine comes in oral capsules containing 25mg, 50mg, or 100mg nitrofurantoin macrocrystals, as well as a 5mg/ml oral suspension. The World Health Organization's List of Essential Medicines, which includes the safest and most effective pharmaceuticals for a health system, includes this substance.In 1953, the medication was first made available to the public. Currently, various manufacturers sell this substance-based brand-name drugs abroad, with the most well-known example being Boehringer Ingelheim's Macrodantina. However, this pharmaceutical substance is also widely available as a generic drug.
How does Nitrofurantoin Works?
The majority of it is filtered out of your blood and into your pee when you take it by mouth. This concentrates the medication exactly among the germs that are causing the infection in the urinary tract. Nitrofurantoin kills bacteria by infiltrating their cells and causing genetic damage. This pharmaceutical remedy is transformed to electron-donating intermediates by microbial nitroreductases that disrupt the TCA cycle as well as DNA, RNA, and protein production. This pharmaceutical substance causes bacteria to die by interfering with their important functions. It achieves therapeutic amounts in the urine quickly and is quickly eliminated. The Cmax of this pharmaceutical substance is 0.875-0.963 mg/L, while the AUC is 2.21-2.42 mg*h/L.3 It has a bioavailability of 38.8-44.3 percent. The retention and persistence of therapeutic levels in the urine are increased when it is taken with food.
Nitrofurantoin is available as a tablet and a solution for oral use. For at least 7 days, it is commonly given two or four times a day. It should be taken with a glass of warm water and food. Take it at the same time each day if possible. Take the label instructions attentively, and if there is anything you don't clear, talk to your physician or pharmacist to explain it to you. Follow the directions for taking this medicine precisely. Need not use more or less of this, or consume it more frequently than your physician has suggested. Before each usage, give the beverage a good shake to ensure that the drug is uniformly distributed. Do not use a household spoon to measure the right amount of liquid for each dose; instead, use a dose-measuring teaspoon or teacup. When you order this medicine, during the first several days of this medication, you should start to feel better. Even if you feel good, keep taking it until the prescription is finished. Your illness will become harder to treat if patients quit taking this medicine too early or miss doses, and the germs could become immune to treatments.
The Wholesale Price of Nitrofurantoin
The retail price for sale of 20 100mg nitrofurantoin tablets in the EU ranges from 4.70 USD to 10.57 USD. Prices can differ from pharmacy to pharmacy you visit.
Navigating our Pharmaceutical Marketplace
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