mometasone furoate Nasal spray 0.05%

Dossier type
CTD
Dossier status
Ready to file
Country of origin
India
GMP approvals
FDA, EU GMP, WHO
Manufacturer #18135
This pharmaceutical company is a global leader specializing in ophthalmic, ENT, and dermatological medications. Founded over four decades ago, they boast a portfolio of over 300 products sold in over 67 countries across regions like the EU, Africa, and Asia. Their key therapeutic areas include dry eyes, eye infections, respiratory tract infections, ear infections, eczema, psoriasis, and acne. They offer various dosage forms such as eye drops, ointments, gels, nasal sprays, creams, and oral medications. The company adheres to international GMP certifications and possesses state-of-the-art manufacturing facilities. Their expertise extends to the development of specialized pharmaceutical excipients, including Stabilized Oxychloro Complex (SOC).

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Mometasone furoate

Mometasone furoate is a medium-strength corticosteroid. This medication treats skin conditions like hay fever, and asthma, Specifically in the prevention rather than in the treatment of asthma attacks. Mometasone furoate can be applied to the skin, inhaled, or used in the nose. The range of skin conditions treated by it includes eczema, psoriasis, allergies, and rash. It controls swelling or inflammation, itching, and redness. Doctors choose the type of Mometasone furoate-based product to be used on the skin condition/area of the body being treated. It was also given to patients unresponsive to less potent corticosteroids, and penile phimosis. In adults and children over 2, the The nasal spray is used to get relief from the symptoms of hay fever also called seasonal allergic rhinitis, and allergies like perennial rhinitis, nasal congestion, discharge, pruritus, and sneezing, and nasal polyps. Mometasone furoate is sold under the brand names Nasonex, Asmanex, Elocon among others. Schering corp first patented Mometasone furoate in 1981. It later came into medical use in 1987 and after the expiry of its initial patent, Mometasone furoate is now sold as a generic medication. It features the top 200 most prescribed medications in the USA medical system.

DOSAGE AND ADMINISTRATION

Mometasone furoate is sold in cream, ointment, and lotion (solution) forms and it can be applied to the skin, inhaled, or used directly in the nose. When using the cream, the user should apply a thin film to the affected skin areas, only once a day. This cream is used only in patients older than 2 years of age. The doctors will recommend discontinuing the therapy when control is achieved. If the patient finds no relief after 2 weeks of use, the primary diagnosis has to be carried out again. Unless directed by a physician, the Cream should not be used with occlusive dressings also in the diaper area if the child is in diapers or plastic pants, as garments sometimes constitute occlusive dressing. This cream is only for topical use. Avoid contact with other parts of the body like the eyes.

The price of Mometasone furoate

This is a relatively inexpensive medicine. The 10gm ointment costs only USD1, branded 5mg cream costs around USD1.2 and the 5ml lotion also costs the same USD1.2. However, this medicine is far more expensive in the USA, where it costs consumes an average retail price of $205.87 for one generic nasal spray of 17g of 50mcg.

How does it work?

Mometasone is a medium-strength corticosteroid. Its actions activate the natural substances in the skin which reduce swelling, redness, and itching. Similar to other topical corticosteroids in its calls, it has the same anti-inflammatory, antipruritic, and vaso-constrictive properties. How it delivers its anti-inflammatory actions, in general, has not yet been fully understood.

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