metyrapone Tablets 250 mg

Dossier type
EU CTD
Dossier status
Ready to file
Country of origin
European Union
GMP approvals
EU GMP
Unavailable markets
Turkey
Manufacturer #15013
The goal when it was founded in the 1990s was to deliver therapeutic answers to medical demands that had previously gone unmet by giant pharmaceutical companies. Almost two decades later, reality has surpassed our expectations. It is a fast-growing OTC company with direct operations in approximately 11 European countries and collaborations that have expanded its product availability to over 90 countries worldwide.

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Metyrapone Manufacturers

A diagnostic medication for determining the function of the hypothalamic-pituitary ACTH axis. In some cases, it's utilized to treat Cushing's syndrome. The enzyme steroid 11-beta-monooxygenase is inhibited. In the diagnosis of Cushing syndrome, it is utilized as a test of the feedback hypothalamic-pituitary system. Metyrapone is a drug that blocks the production of endogenous corticosteroids in the adrenal glands. Metopirone is the brand name for this medicine.

How Does Metyrapone Work?

Metyrapone works by suppressing the 11-ß-hydroxylation process in the adrenal cortex, which reduces cortisol and corticosterone synthesis. The pituitary produces more adrenocorticotropic hormone when the strong inhibitory feedback mechanism exerted by cortisol is removed. Blocking the enzymatic steps that contribute to the synthesis of cortisol and corticosterone. There is a significant rise in adrenocortical production of their immediate antecedents, 11-desoxycortisol, and desoxycorticosterone, that are weak blockers of ACTH release, as well as a commensurate increase in plasma and urine levels of these steroids and their metabolites. Urinary 17-hydroxycorticosteroids or 17-ketogenic steroids can easily be measured to ascertain these metabolites. It is utilized as a diagnostic test because of these activities, with urine 17-OHCS being used as a measure of pituitary ACTH response. It may also inhibit aldosterone production, resulting in moderate natriuresis. Metopirone (metyrapone) belongs to the class of drugs known as adrenal corticosteroid blockers. This drug should be taken orally with milk or even a snack. Take your metyrapone dose at midnight if you're given the single-dose test.

The Wholesale Price of Metyrapone

Almost any drugstore will have this medicine. Depending on the drugstore you visit, Metopirone oral capsule 250 mg costs roughly $615 for a supply of 18 capsules. Prices are only applicable for consumers who pay cash and do not apply to insurance coverage. Pharmaceutical corporations generally support patient assistance programs (PAPs), which provide free or subsidized drugs to low-income, unemployed, or under-insured patients who meet certain criteria.

Navigating Our Pharmaceutical Marketplace

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Quality Assurance

To keep up to the quality standards other than Good Manufacturing Practice approvals that this medicine manufacturers list has, we qualify their companies before they are onboarded on the platform. This allows us to screen Metyrapone manufacturers for the quality of the pharmaceutical products’ dossiers and protect against the risk of possible malpractices.