methadone Tablets 1 mg, 5 mg, 10 mg, 25 mg

Dossier type
CTD
Dossier status
Under development
Country of origin
Canada
GMP approvals
Canada
Comments
Reference product : Metadol (Paladin)
Manufacturer #278

The company has become a prominent partner of the pharmacy community in North America, with the fastest rising market share among generic leaders. It can provide best-in-class supply reliability thanks to production capacity. In more than 50 countries, it's available locally or through corporate partnerships. R&D expenditures range from $40 million to $50 million per year. They are dedicated to maintaining a customer satisfaction rate of over 95% by continuously enhancing supply chain efficiency.

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Methadone Manufacturers

Methadone falls under the drug class Opiates, which is also referred to as narcotic analgesic. It is sold under the brand name Dolophine. This pharmaceutical medicine is used to treat chronic pain in patients who have a terminal disease and in those who cannot take any other pain killers. In addition, Methadone is also used in rehab for individuals who have an opiate addiction, to treat their withdrawal symptoms. Methadone is administered orally, as a pill, tablet under the tongue, or as a liquid. Methadone administration can cause a wide range of side effects such as sedation, constipation, sweating, heat intolerance, dizziness, weakness, dry mouth, nausea, headache, amnesia, and low blood pressure. In certain conditions, this drug is contraindicated, such as current or previous allergy to any of the drug constituents, CNS disorders due to risk of CNS depression, heart diseases, or in conjunction with any other CNS depressant. Methadone should be prescribed with caution in pregnancy, only when the benefits outweigh the risks; as it may harm the baby. Moreover, due to the secretion of Methadone in breast milk, it is advised to consult your doctor before breastfeeding your baby. Methadone was approved by the Food and Drug Administration (FDA) in 1947 for use as a painkiller and treatment of cough. It was approved by FDA for use in opiate-addicted individuals to relieve withdrawal symptoms in 1972. Methadone alters the way your brain and nerve system respond to pain, causing you to feel better. Its effects are more gradual than those of other powerful analgesics such as morphine. If you are in severe pain as a result of an injury, surgery, or long-term sickness, your doctor may prescribe methadone. It also prevents the high caused by medications such as codeine, heroin, hydrocodone, morphine, and oxycodone. It can provide a comparable sensation while preventing withdrawal symptoms and cravings. This is sometimes referred to as replacement therapy. Methadone is available in pill, powder, and liquid forms. You must have a prescription to obtain it. Your doctors will prescribe the appropriate dose for you. They may also alter your dose during treatment. Tell your doctor how you feel after using it. Don't stop taking methadone without first consulting with them. Experts recommend that persons who use methadone to treat an addiction do so for at least a year while they work on recovery.

How does Methadone work?

Methadone works by acting as an antagonist at the NMDA receptors in the brain. NMDA receptors are primarily acted upon by Glutamate, an excitatory neurotransmitter in the CNS. This interaction causes brain stimulation and memory formation and enhancement.

The Cost of Methadone

An online search for the wholesale price for sale of Methadone for distributors will reveal a wide range of costs. It will vary from store to store depending on your visit and the country of the wholesale market. Methadone can vary in price based on your place of purchase and whether you are opting for the generic form of the drug or its brand form. The generic form costs $0.25 to $2.50 per unit, whereas the cost of the brand form is higher.

Navigating our Pharmaceutical Marketplace

Being a global B2B pharmaceutical online marketplace, Pipelinepharma is structured to simplify pharmaceutical deals by providing you with an intuitive interface that is easy to engage with. The selection of Methadone distributors offerings can be narrowed down with the use of filters and easily weighed against one another according to medication prices and commercial terms. The advanced filters help you filter out the countries for these substance manufacturers and this substance Methadone suppliers that you are looking for. These also enable you to check the dossier status of this medicine and the GMP approvals of the different variants of Methadone. Also, each manufacturer or supplier product description contains essential information about this substance including clinical data, stability zones, countries where Methadone is already registered in. Manufacturers also have special, and delivery terms.

Establishing Commercial Ties

If you are a pharmaceutical licensing company or a distributor you can enter into deals or negotiations over these medicine offers with manufacturing companies after completing the free registration process and joining our online marketplace. This helps to ensure that you conclude the pharmaceutical product deal at a reasonable cost and achieve the best cost/benefit ratio for your company while bypassing lengthy sourcing, negotiation, and order process. Once you have finalized a deal, you can look forward to a long-lasting business relationship with the manufacturers Methadone suppliers. This way, the marketplace allows you as a distributor to skip the process of shortlisting product manufacturers every time you are looking for in-licensing or distribution deals.

Quality Assurance

To keep up to the quality standards other than Good Manufacturing Practice approvals that this medicine manufacturers list has, we qualify their companies before they are onboarded on the platform. This allows us to screen Methadone Manufacturers for the quality of the pharmaceutical products’ dossiers and protect against the risk of possible malpractices.