losartan potassium + amlodipine besylate Tablets, film coated 50 mg + 5 mg

Losartan manufacturers

What is Losartan?

Losartan is a medication that belongs to the group of drugs known as angiotensin II receptor blockers (ARBs). Losartan used primarily for the treatment of high blood pressure and to protect kidneys from damage caused by diabetes.

Losartan works by blocking the action of an angiotensin II hormone, which causes blood vessels to narrow and the heart to work harder. By blocking this hormone, Losartan helps to relax blood vessels and lower blood pressure, which can reduce the risk of stroke, heart attack and other complications associated with high blood pressure.

Losartan is typically taken once daily, alone or in combination with other blood pressure medications. It is available in tablet form and only with a prescription from a healthcare provider. 

Losartan forms and dosage

Losartan is available in several forms and dosages, including:

1. Losartan potassium tablets: These are the most common form of Losartan and are available in the following strengths: 25 mg, 50 mg and 100 mg. They are taken by mouth once a day with or without food.
2. Losartan potassium and Hydrochlorothiazide tablets: These tablets contain a combination of Losartan and Hydrochlorothiazide, a diuretic that helps reduce fluid retention and lower blood pressure. They are available in strengths of 50 mg/12.5 mg and 100 mg/25 mg and are taken orally once a day with or without food.
3. Losartan oral solution: This liquid form of Losartan is used for children or adults who have difficulty swallowing tablets. It is available in a 4 mg/mL concentration and is typically taken once a day with or without food.

The dosage of Losartan prescribed by your healthcare provider will depend on several factors, including your age, medical history, and the condition being treated. In general, the usual starting dose of Losartan for adults with hypertension is 50 mg once a day, although some people may need a lower dose to start. 

Losartan patent information

Losartan was initially developed by the pharmaceutical company Merck & Co., Inc. and was first approved by the Food and Drug Administration (FDA) in 1995 in the USA. The original patent for Losartan expired in 2010, which allowed other pharmaceutical companies to begin manufacturing and selling generic versions of the drug.

Since the expiration of the original patent, several generic versions of Losartan have been approved by the FDA and EMA and are available in the United States in Europe.

Losartan wholesale price

Based on wholesalers' information in Europe, the prices of Losartan tablets are the following:

• 25 mg 3.7 EUR per 28-tablet pack in Poland
• 50 mg 1.8-3 EUR per 28-tablet pack in Poland, Lithuania
• 50 mg 8.25-11 EUR per 28-tablet pack in Italy
• 100 mg 5.5-6 EUR per 28-tablet pack in Poland, Lithuania
• 100 mg 10.5-12.5 EUR per 28-tablet pack in Italy

 Prices can vary across different countries within Europe.

Losartan manufacturers and brands

Losartan is a generic medication that is manufactured and sold by several pharmaceutical companies. Some of the manufacturers of Losartan include:

1. Aurobindo Pharma
2. Accord Healthcare
3. Apotex Inc.
4. Lupin Limited
5. Mylan Pharmaceuticals
6. Teva Pharmaceuticals
7. Torrent Pharmaceuticals
8. Zydus Pharmaceuticals

Losartan is also sold under several brand names, including:

1. Cozaar: This is the brand-name version of Losartan that is manufactured by Merck Sharp & Dohme Corp.
2. Hyzaar: This is a combination medication that contains Losartan and Hydrochlorothiazide and is manufactured by Merck Sharp & Dohme Corp.
3. Losartan HCTZ: This is a generic version of Hyzaar that is sold by several different pharmaceutical companies.
4. Losartan Potassium: This is a generic version of Cozaar that is sold by several different pharmaceutical companies.

Losartan hydrochloride and Losartan potassium

Losartan hydrochloride and Losartan potassium are two different salt forms of the same active ingredient, Losartan. The main differences between them are their chemical structures, their solubility, and their dosage strengths.

Chemical structure: Losartan hydrochloride is the hydrochloric acid salt of Losartan, while Losartan potassium is the potassium salt of Losartan. The two salts have different chemical structures, but the active ingredient, Losartan, is the same in both formulations.

Solubility: Losartan potassium is more soluble in water than Losartan hydrochloride. This means that Losartan potassium may dissolve more readily in the body, allowing for more rapid absorption and onset of action.

Dosage strengths: Losartan potassium is available in higher dosage strengths than losartan hydrochloride. For example, Losartan potassium is available in dosage strengths of 50 mg and 100 mg, while Losartan hydrochloride is only available in a 12.5 mg dosage strength.

It is important to note that both formulations are equally effective for treating hypertension. The choice of which salt form of Losartan to use may depend on factors such as availability, cost, and individual patient factors such as their medical history or sensitivity to certain ingredients. 

Connecting to Losartan manufacturers and suppliers

Pipelinepharma is a global pharmaceutical sourcing platform that specializes in helping B2B buyers access a wide range of high-quality, affordable pharmaceutical products. They work with a network of trusted suppliers and manufacturers to ensure that their customers have access to a reliable supply of medications, including Losartan and its various formulations.

To find Losartan products and manufacturers through Pipelinepharma, you can use their online product search tool or connect to their suppliers. The product search tool allows you to search for specific medications of Losartan and filter results by dosage strength, form and manufacturer. 

More than 200 Losartan products are in the Pipelinepharma marketplace, listed under the Generics category. There are products with EU GMP approvals and several ready-to-file EU CTD dossiers.