PipelinePharma Logo

gliclazide Tablets 30 mg

Dossier type
CTD
Dossier status
Ready to file
Country of origin
Vietnam
GMP approvals
WHO
Manufacturer #21654

This CTD dossier owner and manufacturer is a pharmaceutical manufacturer specializing in a range of dosage forms, including tablets (conventional, modified-release, and extended-release) and capsules. They hold GMP certifications aligned with World Health Organization standards, ensuring high-quality production practices. Their key therapy areas are not specified in the provided information. The company's products are likely distributed across multiple regions, given their mention of "international" partners and online presence. While specific details about product patents and licenses are absent, the emphasis on GMP compliance suggests a commitment to regulatory standards.

GLICLAZIDE

Gliclazide is an anti-diabetic medication for the treatment of diabetes mellitus type 2. Gliclazide controls hyperglycemia in gliclazide-responsive diabetes mellitus of stable, mild, non-ketosis prone, type 2 diabetes. As an oral antihyperglycemic agent, it is used for the treatment of non-insulin-dependent diabetes mellitus. It has been classified differently according to its drug properties based on its chemical structure. When launched it belonged to the first-generation of sulfonylurea due to the structural presence of a sulfonamide group able to release a proton and the presence of one aromatic group. However, further studies have shown that Gliclazide is a second-generation sulfonylurea, because it has higher potency and a shorter half-life. Gliclazide is sold under the brand names Diamicron, Diaprel, Azukon, and others. Gliclazide was first patented in 1966 and approved for medical use in 1972. Due to its efficacy and use around the world, it has been listed on the World Health Organization's List of Essential Medicines. Gliclazide is not available for sale in the United States.

Forms and dose:

Gliclazide is available as a tablet and extended-release tablet. In the treatment of type 2 diabetes, the total daily dose recommended varies from 40-320mg. The dose is increased or decreased depending on the response to the therapy. The initial adult dose starts with 40-80mg daily. This can be increased until adequate control is reached. Please note that any single dose should not exceed 160mg. if a patient feels that they need higher doses, it is recommended to take medicine twice a day instead.

The price of Gliclazide:

In India, the lowest price consumers can pay for an 80 mg pill is $0.33. The same supply can cost as low as USD64 for the same supply for medicine.

How does it work?

Gliclazide is in the sulfonylurea family of medications. Its actions increase the release of insulin. It binds to the β cell sulfonylurea receptor subsequently blocking the ATP sensitive potassium channels. The process leads to the closing of channels that leads to a resulting decrease in potassium efflux. This eventually leads to depolarization of the β cells. In the next step, it opens voltage-dependent calcium channels in the β cell resulting in activation of calmodulin. The result of this process is exocytosis of insulin-containing secretory granules.

Finding Gliclazide Manufacturers and Suppliers

The best way to find and gain access to Gliclazide manufacturers and Gliclazide suppliers is to use Pipelinepharma's global B2B online marketplace for medicines and other pharmaceuticals. Normally, finding trusted manufacturers and supplies of specific drugs like Gliclazide can be a time-consuming challenge, but with Pipelinepharma's simple search engine and network of proven partners, the whole process becomes a lot easier. All you need to do to get started is to make use of our integrated search engine and start looking for suppliers or manufacturers of Gliclazide to work with. You can fine-tune your search results using various filters too, letting you search for Gliclazide from specific countries, for example.