Fenticonazole is an imidazole antifungal drug. It is for local use in its nitrate form in the
treatment of vulvovaginal candidiasis. It has been effective in curing a range of fungal
organisms including dermatophyte pathogens, Malassezia furfur, and Candida albicans.
Fenticonazole kills the yeast fungus causing the infection. An occasional bout of vaginal
thrush is an issue many women have caused Candida spp caused the infection. Thrush is
caused by Candida albicans but other types of Candida spp. Have been known to cause
thrush. During the Thrush, the woman feels itching, soreness, and redness outside of the
vagina in addition to a thick, creamy white, odorless vaginal discharge.
Fenticonazole is sold under the brand name Fentizol, Ginna, and Lomexin amongst others.
Fenticonazole is not for sale in the USA and was sold only on prescriptions in the UK, however,
it is not sold in the EU anymore. A Chinese co is the current assignee of the EU agent since
2012. In 2020. Glenmark also released its brand in India.
Dosage and administration
Fenticonazole is sold as a pessary, topical cream, solution, and a vaginal capsule. The regular
treatment includes inserting a 200 mg pessary the vagina at bedtime for 3 nights. Or they can
also use a single 600 mg pessary is inserted once. When used topically, it used as a 2% cream
or solution. If using a vaginal capsule, the user has to gently insert it, as high as possible
using a finger into the vagina at bedtime. The doctor will decide if the user needs it for three
days or one and do remember not to swallow this medicine. When using the cream, it is used
twice a day, morning and the evening, for three days. The user is sold the applicator with the
cream. Using this applicator, the user inserts 5 grams of cream high into her vagina. Use the
applicator, after squeeze cream into it until it is full. After removing the applicator from the
tube once it is full the user then has to gently insert the cream-filled end of the applicator into
the vagina as high as it is comfortable. Once the inserter as high as it goes, the user Pushes
the plunger to release the cream. After this, the user has to remove the applicator and wash it
with warm water and soap.
The Cost of Fenticonazole
In India, the consumers have to pay USD 2 for 2% Cream, whereas 1 vaginal capsule with
600mg medicine costs USD 2. In the ingredients market, the wholesale cost of 1kg is USD
377. Fenticonazole is not for sale in the US, while it was sold in the UK, it has now been
How does Fenticonazole Work?
Fenticonazole has unique antimycotic actions. The show effect in these three ways, first by
inhibiting the secretion of protease acid by Candida albicans, then it goes on to damage to the
cytoplasmic membrane and it also blocks cytochrome oxidases and peroxidizes. These three
combined actions cause fungicide.
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