erythropoietin alfa
Injection, pre-filled syringe
2000 IU, 4000 IU, 10000 IU
- 0.5 ml, 1 ml
Manufacturer usually replies in 16 days
Dossier type
CTD
Dossier status
Ready to file
Country of origin
Vietnam
GMP approvals
Vietnam
Unavailable markets
Philippines
Manufacturer #1535
Manufacturer usually replies in 16 days
Erythropoietin Alfa
Erythropoietin is a therapeutic agent used in treating anemia resulting from chronic kidney
disease and myelodysplasia, from the treatment of cancer like chemotherapy and radiation. It
is produced by recombinant DNA technology in mammalian cell culture. It treats anemia by
increasing the red blood cell count in people with long-term serious chronic kidney failure,
or people getting treated for HIV with zidovudine, and chemotherapy for cancer that does not
involve the bone marrow or blood cells.
Erythropoietin Alfa is given to anemic patients to reduce the need for blood transfusions
before some kinds of planned surgeries with a high risk of blood loss Epoetin alfa actions amek
the bone marrow produces more red blood cells.
Epoetin alfa is human erythropoietin that was authorized by the European Medicines
Agency in 2007 to stimulate erythropoiesis and to treat anemia, associated with chronic
kidney failure and cancer chemotherapy. Amgen manufactured is under the name Epogen,
J& J sells it as Procrit, pursuant to a product license agreement.
Dosage Forms & administration
Epoetin alfa is sold as an injectable solution in concentrations from 2000 units/mL, 3000
units/mL, 4000 units/MLM 10,000 units/mL, 20,000 units/mL and 40,000 units/mL. in the
treatment of Patients with CKD on dialysis, the treatment is initiated when hemoglobin level
drops below <10 g/dL. If its level approaches or >11 g/dL, the user can reduce the dose. The
initial dose is 50-100 units/kg, given through an IV, three times a day. In the treatment of
anemia due to HIV treatment with zidovudine at <4200 mg for the week are given the endogenous
serum of <500 milliunits/mL followed by 100 units/kg, 3 times weekly. If HBG levels don’t
improve in 8 weeks, the dose is increased by 50-100 units for kg, every 1-2 months until
hemoglobin reaches a level sufficient to avoid RBC transfusions. This medication should be
taken closely in relation to the HBG levels in consultation with your doctors.
The Cost of Epoetin Alfa
For years, this medicine cost the US Government, nearly USD 2 billion in making this
medicine affordable. However, the cost has now come down, wherein in the USA, The
consumer cost for the injectable solution of 2000 units/mL is USD $356 for a supply of 10
milliliters. However, it is much cheaper in the developing world. In India, a vial containing
4000IU Inj costs only around USD 12 and can be as high as USD 20.
How does Epoetin Alfa Work?
Erythropoietin is a glycoprotein. Its role is to regulate the production of red blood cells by
stimulating the division and differentiation of committed erythroid progenitor cells in the
bone marrow. Epoetin Alfa is made using recombinant DNA technology in mammalian cell
culture. It works by increasing the red blood cells.
Finding Erythropoietin Alfa Manufacturers and Suppliers
The best way to find and gain access to Erythropoietin Alfa manufacturers and Erythropoietin
Alfa suppliers are to make through Pipelinepharma's global B2B online marketplace for
medicines and other pharmaceuticals.
Normally, finding trusted manufacturers and supplies of specific drugs like Erythropoietin
Alfa can be a time-consuming challenge, but with Pipelinepharma's simple search engine and
a network of proven partners, the whole process becomes a lot easier.
All you need to do to get started is to make use of our integrated search engine and start
looking for suppliers or manufacturers of Erythropoietin Alfa to work with. You can find-
tune your search results using various filters too, letting you search for Erythropoietin Alfa
from specific countries.
https://www.webmd.com/drugs/2/drug-1023/epoetin-alfa-injection/details
https://en.wikipedia.org/wiki/Epoetin_alfa
https://medlineplus.gov/druginfo/meds/a692034.html
https://medlineplus.gov/druginfo/meds/a692034.html
https://medlineplus.gov/druginfo/meds/a692034.html