This pharmaceutical manufacturer boasts decades of experience in the industry, providing a broad range of affordable finished formulations, including prescription drugs, OTC medications, and supplements. They offer turnkey manufacturing, technology transfer, contract development and manufacturing services, as well as co-development and co-marketing options. Key therapy areas include chronic and acute therapies, OTCs, and complex formulations. Dosage forms include tablets, capsules, syrups, powders, liquids, injections, and ointments. They have obtained GMP approvals from regulatory bodies in the EU, North America, and other regions, demonstrating their commitment to quality and compliance. The company's global presence extends to key regions like North America, Asia, and Africa, solidifying their position as a trusted partner in the pharmaceutical industry.
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Dutasteride
Dutasteride is a medication primarily used to treat the symptoms of an enlarged prostate
but it is a long-term medication the benefits of which start showing after using it for a few
months. It is also prescribed for scalp hair loss in men and as a part of hormone therapy in
transgender women. Dutasteride inhibits 5α-reductase, thus classified as an antiandrogen. It
decreases the production of an androgen sex hormone called Dihydrotestosterone.
Dutasteride is sold under the brand names Avodart, Combodart, Duodart among others.
GlaxoSmithKline first patented Dutasteride in 1993 and approved for medical use in 2001. It
is currently sold as a generic medication prescribed to more than one million American
citizens. Since its launch, Its sales has spread to many other countries, including throughout
Europe and South America. The patent protection expired in 2015 and the drug has since
then has been made sold as a generic medication at very low prices in the US and around
the world. In South Korea, it is used in the treatment of scalp hair loss since 2009 and in
Japan since 2015. However, it has not been approved for the same user in the USA.
Dosage Forms and Strengths
Dutasteride is sold as Capsules of 0.5 mg strength. In the treatment of Benign Prostatic
Hyperplasia, the dose is 0.5 mg, taken orally once a day.
The price of Dutasteride
In the USA, the consumer has to pay USD 21 for a supply of 30 oral capsules of 0.5 mg.
Dutasteride is sold at relatively lower prices in other parts of the world. For example, In
India, the supply of 30 tablets of 0.5mg will cost the consumer USD 1.8.
How does Dutasteride work?
Dutasteride is a synthetic 4-azasteroid compound. It is different in that it selectively inhibits
both type 1 and type 2 isoforms of steroid 5 alpha-reductase. This reductase is used to treat
benign prostatic hyperplasia in men with an enlarged prostate. Dutasteride increases the
flow of urine and can also reduce the need for prostate surgery. Dutasteride is prescribed
with Tamsulosin. Dutasteride action stops or prevents the conversion of testosterone to
Dihydrotestosterone.
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