lercanidipine hydrochloride + enalapril maleate Tablets, film coated 10 mg + 20 mg

LERCANIDIPINE HYDROCHLORIDE

Lercanidipine is an antihypertensive drug from the dihydropyridine class of calcium channel blockers, that is, it lowers blood pressure. These medicines’ actions relax and open the blood vessels allowing for blood to circulate more freely. As it lowers the blood pressure, that allows the heart to work more efficiently. It acts slower compared to other dihydropyridines. In patients with high BP, the force of the blood against the artery walls is too high. This increases blood pressure, causing hypertension, technically defined as blood pressure above 140/90. It has often no symptoms but if left unchecked and untreated, it can cause health conditions, such as heart disease and stroke. Taking medicines, besides, a healthy diet and lifestyle are recommended for lowering the blood pressure. Lercanidipine Hydrochloride is sold under the Brand names, Zanidip, Karcanil, Lercapress, among others. Recordati S.A., Chemical and Pharmaceutical Company file for the first patents in the USA in the 1980s. Lercanidipine Hydrochloride was patented in 1984 and approved for medical use in 1997.

Forms and Dosage:

Lercanidipine is available as 10mg and 20mg tablets. The initial dose for most adults is 10mg once a day. The patients are advised to take it only once a day. Also, patients who are allergic to lercanidipine-hydrochloride or any other ingredients of these tablets should not be given this medicine. Also, patients if he is suffering from heart diseases like Untreated heart failure, Obstruction to flow of blood from the heart, Unstable angina and if severe liver or kidney problems should not take this medicine. 

The price of Lercanidipine Hydrochloride:

In Canada and the USA, the consumers have to pay an average retail price of USD1.04 per 20 mg pill, adding up to around 30usd for supply lasting one month. The price is significantly cheaper in the developing and underdeveloped world with the same monthly supply of 30 tablets costs around USD3.

How does Lercanidipine work?

Lercanidipine is a calcium channel blocker. Calcium channel blockers take effect by blocking calcium entering the muscles in the heart and blood vessels. Muscles need calcium to contract, so when the medicine can inhibit the calcium, as a result, the blood pressure lowered. When this medicine is not able to lower the blood pressure at 20 mg, the dose can be increased as per the advice of the doctor.

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