hypromellose Ophthalmic solution 2.5 mg/ml, 5 mg/ml - 10 ml

Country of origin
European Union
GMP approvals
EU GMP
Recommended use
Ophthalmic products
Manufacturer #1858

This company, with a global presence, has been operating for over nine decades, demonstrating its experience and commitment to the healthcare industry. They provide a diverse portfolio of products, including prescription medications, healthcare solutions, and animal nutrition products. Their focus is on areas like allergies, gastrointestinal health, and immune system support. Key dosage forms include solids, liquids, and orals. They have manufacturing facilities in the EU and hold EU GMP approvals. They actively engage in research and development, investing in new molecules and clinical trials. Their commitment to sustainability is reflected in their focus on reducing environmental impact and promoting social responsibility. They operate in key regions including Europe, North America, and Latin America. While specific countries are not mentioned, the company emphasizes its international reach through a global network of partners.

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HYPROMELLOSE

Hypromellose is popularly called artificial tears. It prevents corneal damage in patients with kerato- conjunctivitis sicca accompanying rheumatoid arthritis, xerophthalmias, or keratitis. It moistens hard contact lenses and lubricates artificial eyes during Gonioscopy procedures. Hypromellose actions provide relief of dry eye conditions immediate. These include dry eye conditions associated with the use of TVs, infrequent blinking, some therapies, pollution, and a dry atmosphere. It is used as eye drops and a component of controlled-delivery in oral medicaments. It is used in HPMC matrices and oral controlled delivery systems. It is also used in a wide range of commercial products. As a food additive, Hypromellose is used as a thickening, suspending agent emulsifier, and an animal gelatin alternative. Hypromellose has other uses such as acting as a thickening agent, binder, hydrophilic matrix material, and film former. Hypromellose is sold under the brand names Hymelose, Hyprosol, Ikleen amongst others. Yea-Sheng Yang filed for the first patent in relation to Hypromellose in 2002. Noack Robert M. later filed a patent for Oral extended-release tablets and methods of making and using the same in 2002. Since it is essential to mix ingredients, Hypromellose is involved in several formulations and patents by several companies around the world.

Dosage and administration

Hypromellose is sold as oral & ophthalmic solution in 18 mg/1mL and 25 mg/1mL strengths. The dose for adults, children, and the elderly is one or two drops topically instilled into the eye, three times a day or directed by the doctors.

The price of Hypromellose

In the USA, consumers have to pay an average retail price of USD 24.30 for a supply of 15 milliliters. The price of 0.3%/ml eye drops cost USD 0.35 for a supply of 10ml.

How does it work?

Hypromellose increases corneal wetting by the stabilization and thickening of the precorneal tear film. Its actions also prolong the tear film breakdown time, which is very short in people with dry eye conditions. Its ingredients also lubricate and protect the eye. Hypromellose’s surface-active properties stabilize the tear film and increase tear viscosity, resulting in prevention and delay in tear evaporation and delay tear drainage. In patients with dry eyes caused by mucin deficiency, its surface activity and its adsorptive capacity make hypromellose ideal for use. Hypromellose actions create an aqueous solution, a reduced surface tension, and an increased level of viscosity. Hypromellose provides ample moisture to the cornea and conjunctiva.

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