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1 products found

pp-043

Solution for infusion

Dossier type
CTD
Dossier status
Under development
Country of origin
South Korea
Comments
Indication: Advanced or metastatic solid tumours (e.g., non-small cell lung cancer, head & neck squamous cell carcinoma, renal cell carcinoma, urothelial carcinoma, malignant melanoma). Clinical stage / status: Phase 1 ( trial in the USA). Mechanism / differentiating features: Human monoclonal antibody targeting LILRB1 (Leukocyte Immunoglobulin-Like Receptor B1) — blocks the binding of tumour-expressed HLA-G to LILRB1 on immune cells, thereby activating multiple immune cell types (T cells, NK cells, macrophages) simultaneously. Route / form: Intravenous infusion of the monoclonal antibody. Differentiation / unmet need: unique mechanism engaging multiple immune cell types rather than just T-cells; addresses solid tumor patients who have progressed on standard treatments.
Manufacturer #16907

This South Korea–based life-sciences organization develops a portfolio of small-molecule and biologic therapeutics, with a strategic focus on oncology, immunology, and metabolic diseases. Its pharmaceutical R&D is supported by global clinical programs and collaborations aimed at advancing first-in-class and best-in-class candidates. The group also maintains established therapeutic franchises and leverages international partnerships to expand its presence in the global healthcare market.

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