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acarbose

Tablets for oral solution 25 mg, 50 mg

Dossier type
CTD
Dossier status
Ready to file
Country of origin
India
GMP approvals
WHO
Manufacturer #19735
The company is a leading pharmaceutical manufacturer and supplier, specializing in providing high-quality medicines to semi-regulated and non-regulated markets worldwide. Based in Asia, the company is committed to delivering innovative healthcare products at competitive prices while continuously expanding its product portfolio across new therapeutic segments. With a strong network of reputable contract manufacturers globally, the company ensures compliance with stringent regulatory standards and environmental guidelines. The company's mission is to improve global health and well-being through knowledge-based products, aiming to be the preferred partner in the healthcare industry by consistently meeting high regulatory requirements.

Manufacturer usually replies in 8 days

acarbose

Tablets 25 mg, 50 mg

Dossier type
EU CTD
Dossier status
Ready to file
Country of origin
India
GMP approvals
EU GMP
Manufacturer #19279

This company, based in South Asia, has been operating for over two decades, specializing in pharmaceuticals. It produces a wide range of products, including prescription drugs, over-the-counter medications, intravenous infusions, and bulk drug ingredients. They operate in both regulated and unregulated markets, exporting to regions like Europe, the Far East, and Latin America. The company boasts world-class manufacturing facilities, adhering to Good Manufacturing Practices (GMP) standards. While not explicitly stating specific therapy areas, their focus on IV solutions and bulk drug ingredients suggests a concentration on areas like oncology, cardiology, and critical care. The company's production lines include a variety of dosage forms such as solids, liquids, and injectables.

Manufacturer usually replies in 41 days

acarbose

Tablets 25 mg, 50 mg, 100 mg

Dossier type
CTD
Dossier status
Ready to file
Country of origin
India
GMP approvals
EU GMP
Manufacturer #31580

Established in 1990, this Indian manufacturer employs approximately 3,065 individuals and specializes in developing and manufacturing IP-led niche finished dosage formulations. As a CTD dossier owner and manufacturer, it holds GMP certifications from major regulatory authorities, including the US FDA, EU-GMP, Health Canada, and UK MHRA, ensuring compliance with stringent international quality standards. The company operates eight manufacturing units across India, Singapore, Italy, the United States, and Kenya, producing a range of products, including soft gelatin capsules, tablets, and ointments. As a CTD dossier owner and manufacturer, its products are distributed in over 100 countries worldwide.

Manufacturer usually replies in 33 days

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Acarbose

Acarbose belongs to the class of anti-diabetic drugs and it is used to treat type 2 diabetes. It is also used in some countries to treat prediabetes. It works best as a part of the larger proper diet and exercise program. It is vital that the high blood sugar is brought under control because it helps prevent kidney damage, blindness, nerve problems, and other dangerous complications arising out of diabetes. It is also important medicine because the control of diabetes lessens the risk of a heart attack or stroke. Acarbose is a starch blocker, and working by inhibiting the alpha glucosidase, an intestinal enzyme that releases glucose from larger carbohydrates.
Acarbose is sold as a generic in Europe and China under the brand name Glucobay (Bayer AG) and in North America as Precose (Bayer Pharmaceuticals), and in Canada as Prandase (Bayer AG).
In 1990, Bayer AG introduced, the first drug of new type of oral antidiabetic commercialized under the name of acarbose (Glucobay®)30 . Acarbose was first approved for medical use in the United States in 1995 and was the first alpha-glucosidase inhibitor.

Dosing

Acarbose should be taken before the start of main meals as it prevents the digestion of complex carbohydrates, Even the amount of complex carbohydrates in the meal effects the efficacy of Acarbose. An Adult is given a dose of 25 mg 3 times daily, increasing to 100 mg 3 times a day. The maximum daily dosage however the maximum dose per day is 600 mg.

Cost of Acarbose

The cost of Acarbose is cheaper in developing than the developed world. A standard tablet with the strength of 500mg cost USD for generic makers and USD35 for reputed brands. Recent changes in regulation in china bringing down the prices of drugs meant that Acarbose is now available at 93% discount costing only USD1 for one tablet of 50mg.

How does Acarbose work?

Acarbose blocks glycoside hydrolases which are needed in digestion of carbohydrates, specifically, alpha-glucosidase enzymes in the brush border of the small intestines, and pancreatic alpha-amylase. Acarbose works in intestines by slowing down the breakdown and absorption of complex carbohydrates from diet. This effect helps control the rise of blood sugar levels after a meal. Acarbose specifically inhibits those enzymes which help to digest carbohydrates. The Inhibition these enzyme systems decreases the rate of digestion of complex carbohydrates, as are result less glucose is absorbed because the carbohydrates are not broken down into glucose molecules. In patients of type 2 diabities, the short-term effect is to decrease current blood glucose levels and the long-term effect is a reduction in HbA1c level. This is vital because the slowing of food digestion helps keep blood glucose from rising very high after meals.

Finding Acarbose Manufacturers and Suppliers

The process of finding trusted Acarbose manufacturers and Acarbose suppliers can be made quicker and more accessible by using Pipelinepharma's online platform, a B2B marketplace that lets you finalize the deals of pharmaceutical products in a matter of a few clicks. Also, it is an easy to use online platform to grow your business opportunities.
The robust search engine makes it convenient to search for manufacturers and suppliers of Acarbose. The search can be further refined with industry-specific filters such as dossier type, country of origin, GMP approvals, and search criteria for Wholesaler, etc. helping to get in contact with the preferred manufacturer and supplier readily.

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